Pathophysiology NUR231 Exam |
Questions Solved 100% Correct
IgG - ✔most abundant, pivotal in 2nd response, activator of Ag-Ab commpliment system
IgM - ✔1st responder, big, activator of Ag-Ab /commpliment system
IgA - ✔tears, colostrum, secretions
IgE - ✔release histamines, allergic response
IgD - ✔bound to B-cells, antigen receptor
Cell Mediated (T/B cell) - ✔humoral-Bcells/antibodies, cell mediated T-cells
Phagocytosis - ✔eat foreign material, present foreign material to the immune system
Complement System - ✔activate inflammatory response, plasma protein cascade activates
and binds to Ag-Ab complex causing apoptosis
Specific Immuntity - ✔humoral/cell mediated
Primary Immune Response - ✔humoral immunity dominated by IgM, smaller amounts of IgG
,Secondary Immune Response - ✔humoral response of large production of IgG
Passive Immunity - ✔borrow someone else's Ig, body does not have immune response,
no memory B/T cells
Active Immunity - ✔body undergoes immune response and makes B/T cells and stores
memory cells
Natural Active Immunity - ✔immunity acquired through illness
Artificial Active Immuntity - ✔immunity acquired through vaccination
Natural Passive Immuntity - ✔immunity acquired through placenta, colostrum
Artificial Passive Immunity - ✔immunity acquired from antibodies produced from
another organism, antivenin, rabies
Type I :Allergic Reactions - ✔allergies, anaphylaxis, histamine, can cause hypoxia - insect
sting, antibiotics, foods, anesthetics
Type II: Cytotoxic Hypersensitivity - ✔ABO incompatibility, IgG mediated donor
blood destruction, inflammatory response, alloimmunity
Type III: Immune Complex Hypersinsitivity - ✔Ag-Ab not removed by compliment,
deposited in tissue, later compliment activation destroys tissue - serum sickness, rheumatic
fever, autoimmune disorders - rheumatoid arthritis, MS, Lupus
Type IV: Cell-Mediated/Delayed Hypersensitivity - ✔mediated by sensitized T-cells, delayed
response, T-cell destroy tissue containing antigen, TB(mantoux test), contact dermatitis, poison
ivy, graft host rejection/tissue rejection (alloimunity)
, Anaphylactic Shock - ✔immediate body wide hypersensitive reaction
respiratory problems (burns) - ✔difficulty breathing, may have inhaled hot air and
burned trachea
pain (burns) - ✔occurs with burns due to inflamation
infection (burns) - ✔loss of skin, stress
metabolic needs (burns) - ✔increased needs, high caloric intake
superficial partial-thickness burn - ✔does not penetrate past epidermis, no blisters, sun burn
deep partial-thickness burn - ✔complete epidermis and part of dermis affected, blistering
full-thickness burn - ✔damage through epidermis, dermis, connective tissue, nerves, bones
etc, requires skin graft
local - ✔at site, rubor, calor, swelling, edema, pain, loss of function
systemic - ✔body wide, general/vague: fever, malaise, fatigue, headache, anorexia
gram - - ✔less peptidoglycan in cell wall, release endotoxins, does not stain
gram + - ✔peptidoglycan in cell wall, stains, actively releases exotoxins
HIV - ✔RNA retro virus, infects T-helper cells