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ONS ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATION EXAM WITH ALL MUST KNOWS
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ONS ONCC CHEMOTHERAPY IMMUNOTHERAPY CERTIFICATION EXAM WITH ALL MUST KNOWS
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ONS/ONCC CHEMOTHERAPYIMMUNOTHERAPY CERTIFICATION
EXAM WITH ALL MUST KNOWS…..
Lesson B1: BFoundations Bto BSet Bthe BStage B- Bcorrect Banswer-
Focusing Bon BCellular BStructure Band BFunction B- Bcorrect Banswer-
The BNormal BCell BCycle B- Bcorrect Banswer--The Bcell Bcycle Brefers Bto Bthe
Bordered Bseres Bof Bprocesses Bof BDNA Breplication Band Bmitosis, Bor Bcell Bdivision
-Cell Bnucleus Bregulates Bthese Bprocesses Bby Bgathering Band Bprocessing
Bcomplexes Bmolecular Binformation
Interphase Band BMitotic BPhase B- Bcorrect Banswer-Cell Bdivision Bproduces Btwo
Bidentical Bcells Bthrough Bthese Btwo Bmajor Bphases
During Binterphase: B- Bcorrect Banswer-Cell Bgrows Band BDNA Bis Breplicated
Bthrough Bthe Bfollowing Bthree Bsteps:
,1: BFirst Bgrowth Bphase B(G1 Bor Bfirst Bgap)
2: BSynthesis Bphase B(S Bphase)
3:Mitotic BPhse B(M Bphase)
First BGrowth BPhase B(G1 Bor Bfirst Bgap) B- Bcorrect Banswer--cells Bincrease Bin Bsize
-reproduce BRNA
-"quality Bassurance" Btest Bthat Bthe Bcell Bwill Bbe Bready Bto Bsynthesis BDNA
-Length Bof Btime Bis Bvariable, Bcan Bbe Bfrom Bhours Bto Bdays
Synthesis BPhase B(S Bphase) B- Bcorrect Banswer--DNA Breplicates
-Results Bin Bthe Bformation Bof Bidentical Bpairs Bof BDNA B(chromatids)
-which Bare Battached Ba Bt Bthe Bcentromere
-lasts B2-10 Bhours
Mitotic BPhase B(M Bphase) B- Bcorrect Banswer--Replicated Bchromosomes Bare
Baligned, Bseparated, Band Bmove Binto B2 Bnew, Bidentical Bdaughter Bcells
-takes Babout B30-60 Bminutes
Major Bpoints Bof Bcell Bregulation Bare Bentry Band Bexit Bfrom B- Bcorrect Banswer--G1
Bcheckpoint
-S BPhase
-G2 Bcheckpoint
-M Bphase
Restriction BPoint B- Bcorrect Banswer--The Btransition Bfrom Bthe Bresting Bphase Binto
Ban Bactively Bdividing Bphase B(G0-G1) Bis Ba Bpoint Bwhere Bcellular Btransformation
Bcan Boccur B
-During Bthis Btime, Bcells Bpass Bthrough Ba Btransition Bphase Bknown Bas Ba
Brestriction Bpoint
-Extracellular Bgrowth Bfactors Btrigger Breentry Binto BG1, Band BGF Bare Brequired Bto
Bsend Bthe Bcells Bpast Bthe Brestriction Bpoint, Bor Bthe Bpoint Bof Bno Breturn
G0 BPhase B(resting Bphase) B- Bcorrect Banswer--After Bmitosis, Bcells Bmay Benter
Bback Binto Bthe BG1 Bphase Bor Bgo Binto Ba Bresting Bphase, Bknown Bas BG0
, -Most Bcells Bin Bthe Bhuman Bbody Breside Bin BG0
-Exceptions Bto Bthis Bare Bthose Bthat Bare B(Resting Bin BG0 Bphase) B- Bcorrect
Banswer--Exceptions Bto Bthis Bare Bthose Bthat Bare Bmetabollically Bactive, Bsuch Bas
B
-granulocytes B
-and Bthe Bepithelium Bof Bthe BGI Btract
Cell BCycling BTime B- Bcorrect Banswer-Amount Bof Btime Bfrom Bmitosis Bto Bmitosis
Cell Bcycle Bvideo Band Bimage B- Bcorrect
Banswer-http://highered.mheducation.com/sites/0072495855/student_view0/
chapter2/animation__how_the_cell_cycle_works.html
Check Bpoints Bin Bthe BCell BCycle: BKeeping Bit BAll BUnder BControl B- Bcorrect
Banswer--The Bcell Bcycle Bis Bcarefully Bcontrolled Bthrough Ba Bseries Bof
Bcheckpoints
-Variation Bin Bduplication Bor Bdistribution Bof Bchromosomes Bduring Bcell Bdivision
Bcan Balter Bthe Bgenetic Binformation Bpassed Bon Bto Bdaughter Bcells, Bleading Bto
Bcellular Bdysfunction Band Bdisease, Bsuch Bas Bcancer
-These Bcheckpoints Bmonitor Bfor BDNA Bintegrity Band Bcontrol Bprogression Bthrough
Bmitosis
Progression Bthrough Bthe Bcell Bcycle Bis Bcontrolled Bthrough Btwo Bproteins: B-
Bcorrect Banswer-1. Bcyclines B(D, BE, BA, BB)
2. BCyclin-dependent Bkinases B(CDKs)
-Cyclin-CDK Bcomplex Ballows Bthe Bcell Bto Bprogress Bthrough Beach Bphase Bof Bthe
Bcell Bcycle
Locations Bof Bproteins BCyclins B(D, BE, BA, BB) Band BCDKs B- Bcorrect Banswer--(G0-
G1) B: BCyclin BD Band BCDK B4/6
-Early BS: BCyclin BE Band BCDK B1/2
-Late BS: BCyclin BA Band BCDK B1/2
-G2: BCDK B1/2 Band Bcyclin BA
-Before BM: BCDK B1 Band BCyclin BB
Inhibitory Bproteins B- Bcorrect Banswer--prevent Bprogression Bof Bthe Bcycle Bwhen
BDNA Bdamage Bis Bdetected
-An Bexample Bof Ban Binhibitory Bprotein Bis Bp53 B(AKA BTP53)
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