BIOCHEMISTRY MIDTERM EXAMINATION QUESTIONS AND ANSWERS. ALL MIDTERM EXAM REVISION QUESTIONS AND CORRECT ANSWERS (GRADED A+) (100% GUARANTEE) (2024 UPDATE)
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Course
Biochem
Institution
Biochem
Fatty acids synthesized in the liver used to produce triacyclglycerols which are transported by
VLDL particles to peripheral tissues for storage. Adipose is the primary tissue used for storage of
triacyclglycerols
Which of the following is an insulin insensitive GLUT transporter found primarily ...
Fatty acids synthesized in the liver used to produce triacyclglycerols which are transported by
VLDL particles to peripheral tissues for storage. Adipose is the primary tissue used for storage of
triacyclglycerols
Which of the following is an insulin insensitive GLUT transporter found primarily on the liver?
1. GLUT1
2. GLUT2
3. GLUT3
4. GLUT4 - ANSWER- 2. GLUT2
The glucose uptake by the liver is insulin insensitive and facilitated by GLUT 2 transporters.
Which of the following best describes the net effect of the 8 steps of the TCA cycle?
1. This process completely oxidizes an acetyl group to carbon dioxide.
2. This process directly converts pyruvate to succinate.
3. This process produces NAD+ and Q.
4. This process directly produces ATP for the cell. - ANSWER- 1. This process completely
oxidizes an acetyl group to carbon dioxide.
,The TCA cycle does not directly produce large amounts of ATP but it produces NADH which is
used to produce ATP in the ETC. The cycle itself oxidizes acetyl-coA and releases CO2.
Cleavage of fructose 1-phosphate into dihydroxyacetone-phosphate and glyceraldehyde is
facilitated by which enzyme?
1. Ketolase
2. Fructohydrolase
3. Aldolase
4. Fructokinase - ANSWER- 3. Aldolase
Fructose 1-phosphate is cleaved by aldolase B and these products can enter into the glycolytic
pathway.
High levels of activity of the non-oxidative portion of the pentose pathway will produce
intermediates of which of the following pathways?
1. Glycolysis
2. TCA cycle
3. Cori cycle
4. Glycogen synthesis - ANSWER- 1. Glycolysis
The non-oxidative portion of the pathway can contribute to the increased synthesis of fructose 6-
phosphate and glyceraldehyde 3-phosphate.
Within the red blood cell, NADPH is used for which of the following processes
,1. To re-reduce glutathione
2. To generate ATP
3. For the synthesis of glucose
4. For fatty acid synthesis - ANSWER- 1. To re-reduce glutathione
NAPDH is used for reductive biosynthetic pathways. In the red blood cells, the pentose pathway
is the only means of generating NADPH, therefore impairment of the pathway will manifest
symptoms related to red blood cell dysfunction.
A patient is found to have a rare disease in which the secretory function of the α-cells of the
pancreas is impaired. As a consequence, glucagon cannot be secreted. Direct stimulation of which
of the following pathways in liver will be impaired? - ANSWER- Gluconeogenesis
Glucagon is secreted from α-cells in the pancreas in the fasted state. It primarily activates fasted
state pathways while directly or indirectly inhibition fed state pathways. Gluconeogenesis is the
only fasted state pathway on this list.
Shortly after a meal, there will be increased activity in which of the following pathways as a result
of increased insulin? - ANSWER- Glycolysis
Insulin is an anabolic hormone and increases glucose uptake by most tissues as well as flux through
glycolysis. It would also increase other anabolic pathways such as glycogen synthesis, fatty acid
synthesis and cholesterol synthesis.
Glycolysis provides intermediates that can be used to make other necessary substrates. One
example of this is the direct conversion of pyruvate to which of the following amino acids?
, a. Glutamate
b. Proline
c. Alanine
d. Threonine - ANSWER- c. alanine
Which of the following compounds allosterically activates phosphofructokinase-1 (PFK1)?
a. Citrate
b. Glycerol
c. NADH
d. Fructose 2,6-bisphosphate - ANSWER- d. Fructose 2,6-bisphosphate
Which of the following best describes the net effect of the 8 steps of the TCA cycle?
a. This process completely oxidizes an acetyl group to carbon dioxide.
b. This process directly converts pyruvate to succinate.
c. This process produces NAD+ and Q.
d. This process directly produces ATP for the cell. - ANSWER- a. This process completely
oxidizes an acetyl group to carbon dioxide.
TCA cycle intermediates are always being removed for various reasons but the cycle does not run
out of intermediates and stop. This is because the TCA cycle can replenish intermediates through
which of the following?
a. From acetyl CoA
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