Psychopharm - Pharmacodynamics Review Questions with Complete Solutions Graded A+
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Course
Psychopharm - Pharmacodynamics
Institution
Psychopharm - Pharmacodynamics
Psychopharm - Pharmacodynamics Review Questions with Complete Solutions Graded A+
pharmacodynamics - Answers all drug effects, beneficial and undesired, as well as the body's compensatory homeostatic adjustments to the presence of a drug
dose - Answers measured quantity of a medicine to be taken ...
Psychopharm - Pharmacodynamics Review Questions with Complete Solutions Graded A+
pharmacodynamics - Answers all drug effects, beneficial and undesired, as well as the body's
compensatory homeostatic adjustments to the presence of a drug
dose - Answers measured quantity of a medicine to be taken at 1 time or at stated intervals
concentration - Answers - amt of drug or other substance in a given volume
- amt of drug over unit of volume, i.e. 20mg/ml
threshold dose - Answers a dose of drug just sufficient to produce a pre-selected effect
In pharmacodynamics, what does the "potency" of a drug refer to? - Answers - the relative dose
required to achieve a given effect
- used as a way to compare similar drugs
- ex: Haldol is more potent than Thorazine because it only takes 5mg of Haldol to achieve the same
effects as 100mg of Thorazine
What is the median effective dose of a drug? - Answers the dose of a drug predicted to produce a
characteristic effect in 50% of the subjects to whom the dose is given
What is the median lethal dose of a drug? - Answers dose which produces death in 50% of a (test)
population
therapeutic index of a drug - Answers - the ratio of the median lethal dose to the median effective dose
- measures the safety of a drug
- the higher the therapeutic index, the safer the drug
What is meant by "affinity" when speaking of drug-receptor interactions? - Answers relative strength of
chemical forces that cause the drug to bind to the receptor
What is meant by "efficacy" when speaking of drug-receptor interactions? - Answers - the power of the
drug, through the information encoded in its chemical structure, to activate the receptor when the drug
binds to it
- how good the drug is at making a certain response from the cell
agonist - Answers drugs that produce the same effects, when they bind to a neuroreceptor as does the
natural neurotransmitter
antagonist - Answers - drugs that block the actions of natural neurotransmitters/agonists, partial
agonists, and inverse agonists that are active at the receptor
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