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Adult Psychiatry Part 1 SPMM HiYield Paper B – Qs & As (Graded A+)
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Adult Psychiatry Part 1 SPMM HiYield Paper B – Qs & As (Graded A+)
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Adult Psychiatry Part 1 SPMM HiYield Paper B – Qs &As (Graded A+)
Depot that compares favourably with others in terms of symptom control but
produces higher EPSEs burden? Right Ans - Zuclopenthixol depot
Male patient on clozapine has gained 20kg in 3 months although his psychotic
symptoms are well controlled. Next step? Right Ans - Lifestyle modification
Risk of Tardive Dyskinesia for oral and depot formulations is? Right Ans -
The same
Antipsychotic most associated with hyperglycaemia and dyslipidaemia?
Right Ans - Olanzapine
Best evidence antipsychotic reducing suicidality in F20? Right Ans -
Clozapine
Evidence based management for body dysmorphic disorder? Right Ans -
Fluoxetine (Triple blind study showed response after 8-12 weeks at
increasing doses)
Is a lower dose required for maintenance than an acute episode of psychosis?
Right Ans - No evidence in favour of lower doses
What has been trialled as an add-on Therapy with antipsychotics for negative
symptoms in patients with deficit syndrome of schizophrenia? Right Ans -
D-cycloserine
Which FGA was used in CATIE? Right Ans - Perphenazine (similar to
Chlorpromazine but fewer incidences of EPSEs)
Best evidence for reducing aggression in history of F20 for 20 years? Right
Ans - Clozapine (anti-aggressive effect appears to be separate from the
antipsychotic and sedative actions)
Poor prognostic factors in F20 (4) Right Ans - Social isolation, living alone,
soft neurological signs and young/insidious onset
, Psychosocial interventions with established evidence in F20? (4) Right Ans
- CBT, Family Therapy, Psychoeducation, Vocational Rehabilitation
Obstetric events associated with increased risk of F20? (4) Right Ans -
Foetal hypoxia at delivery, LBW, Pregnancy induced HTN, Premature rupture
of membranes
Characteristic feature of simple schizophrenia? Right Ans - Social
Withdrawal
Single most important factor that increases risk of hospitalisation of the
mentally ill? Right Ans - Being non-compliant
Conceptual disorganisation of PANSS is coded as a? Right Ans - Positive
symptom
Risk of F20 in a child if both parents have F20? Right Ans - 40-50%
Available evidence for treating cognitive symptoms associated with F20?
Right Ans - No conclusive evidence for the use of a specific agent (cognitive
improvements observed in RCTs with SGAs overinflated by Hawthorne effect)
SSRI-induced sexual dysfunction occurs due to? Right Ans - 5HT2
stimulation
Strategy with better efficacy with respect to admin of ECT? Right Ans -
Using higher dose instead of lower dose current
Scale to screen for depression in a patient with OCD by a community mental
health worker? Right Ans - BDI (self-rated) - trained clinicians can use
HAMD to Ax severity and presence of depression in OCD
55yo taking phenelzine and escitalopram has an increased risk of? Right
Ans - Serotonin Syndrome (MAOI and SSRI must be avoided at all costs)
Attrition risks according to STAR*D trial? (3) Right Ans - Younger age, less
education, higher perceived mental health functioning (experience with prior
depressive episode associated with less attrition)
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