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NR565/ NR 565 Advanced Pharmacology Care of the Fundamentals Final Exam Review: Week 5 & 6 & 7 & 8 Questions and Verified Answers Chamberlain ||Complete A+ Guide $15.49
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NR565/ NR 565 Advanced Pharmacology Care of the Fundamentals Final Exam Review: Week 5 & 6 & 7 & 8 Questions and Verified Answers Chamberlain ||Complete A+ Guide
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NR565/ NR 565 Advanced Pharmacology Care of the Fundamentals Final Exam Review: Week 5 & 6 & 7 & 8 Questions and Verified Answers Chamberlain ||Complete A+ Guide

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  • October 18, 2024
  • 47
  • 2024/2025
  • Exam (elaborations)
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NR565/ NR 565 Advanced Pharmacology Care of the
Fundamentals Final Exam Review: Week 5 & 6 & 7 & 8
Questions and Verified Answers Chamberlain



1. Signs and symptoms of hypothyroidism:Face is pale, puffy, and expression- less.
v v v v v v v v v v




Skin is cold and dry.
v v v v




hair is brittle, and hair loss occurs.
v v v v v v




Heart rate and temperature are lowered. The patient lethargy, fatigue, and intoler-
v v v v v v v v v v v




ance to cold.
v v v




Mentation may be impaired. v v v




2. Signs and symptoms of hyperthyroidism:Heart Rate is Rapid; Possible ar-
v v v v v v v v v




rhythmia/angina v




Nervousness, insomnia, rapid thought flow, and rapid speech
v v v v v v v




Skeletal muscles may weaken and atrophy
v v v v v v




Metabolic rate is raised, resulting in increased heat production, increased body
v v v v v v v v v v




temperature, intolerance to heat, and skin that is warm and moist
v v v v v v v v v v v




Weight loss occurs if caloric intake fails to match the increase in metabolic rate
v v v v v v v v v v v v v

, v/

21




1




3. Severe hypothyroidism:Myxedema
v




4. Hypothyroid Treatment:Levothyroxine is the drug of choice for
v v v v v v v




v most patients who require thyroid hormone replacement.
v v v v v v




5. Levothyroxine (Synthroid) Therapeutic Goal:Resolution of signs and symp-
v v v v v v v




v toms of hypothyroidism and restoration of normal laboratory values for serum
v v v v v v v v v v




v thyroid-stimulating hormone (TSH) and free thyroxine (T4).
v v v v v v




6. Major forms of hyperthyroidism:Graves disease and toxic nodular goiter
v v v v v v v v




v (also known as Plummer disease).
v v v v




7. Graves Disease:Most common cause of excessive thyroid hormone secretion
v v v v v v v v




8. What adjunctive therapy is good to prescribe to control symptoms of
v v v v v v v v v v




v hyper- thyroidism other than thyroid specific medications?:²-Blockers and
v v v v v v v




v nonradioac- tive iodine may be used as adjunctive therapy.
v v v v v v v v




²-Blockers suppress tachycardia by blocking ²-receptors on the heart.
v v v v v v v v




v Nonradioactive iodine inhibits synthesis and release of thyroid hormones.
v v v v v v v v

,9. Monitoring needs and intervals for Levothyroxine:Check TSH 6-8 weeks after
v v v v v v v v v



initiating therapy and after any dosage change.
v v v v v v




Check TSH at least once a year after serum TSH is stabilized.
v v v v v v v v v v v




10. Hyperthyroid Treatment:thionamide drugs—methimazole and propylthiouracil
v v v v




v (PTU)—suppress synthesis of thyroid hormones. v v v v




11. Methimazole Therapeutic Goal:(1) reduction of thyroid hormone
v v v v v v




v production in Graves' disease, (2) control of hyperthyroidism until the effects of
v v v v v v v v v v v




v radiation on the thyroid become manifest, (3) suppression of thyroid hormone
v v v v v v v v v v




v production before subtotal thyroidectomy, (4) treatment of thyrotoxic crisis.
v v v v v v v v

, 12. Monitoring needs and intervals v v v v for Methimazole:Check CBC with
v v v




v differential if signs or symptoms of infection. Check LFTs if signs or symptoms of
v v v v v v v v v v v v v




v liver dysfunc- tion.
v v




13. High Risk Patients for Methimazole:Should be avoided in the first trimester
v v v v v v v v v v




v of pregnancy.
v




14. Methimazole Toxicity:Agranulocytosis is the most dangerous toxicity. v v v v v v




15. PTU High Risk Warning:Carries a risk for liver toxicity. Although rare, the
v v v v v v v v v v v




v FDA recommends against using as a first-line treatment due to potential for
v v v v v v v v v v v




v hepatic toxicity. v




16. Effects of maternal hypothyroidism on offspring and appropriate patient
v v v v v v v v




v teaching related to need for treatment.:Can cause delay in mental
v v v v v v v v v




v development and derangement of growth. In the absence of thyroid hormones,
v v v v v v v v v v




v the child develops a large and protruding tongue, potbelly, and dwarfish stature.
v v v v v v v v v v v




v Development of the nervous system, bones, teeth, and muscles is impaired.
v v v v v v v v v v




17. Congenital Hypothyroidism Treatment:requires replacement therapy with
v v v v v




v thyroid hormones. If treatment is initiated within a few days of birth, physical
v v v v v v v v v v v v




v and mental development will be normal.
v v v v v

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