MCB Exam 2 Rats Questions With Correct
Answers
Extensive digestion of chromatin with micrococcal nuclease was found to yield particles called
nucleosome core particles that appear as beads when viewed by electron microscopy. Which of
the following is not found in the nucleosome core particle?
...
Extensive digestion of chromatin with micrococcal nuclease was found to yield particles called
nucleosome core particles that appear as beads when viewed by electron microscopy. Which of
the following is not found in the nucleosome core particle?
a. Two molecules of H2A protein
b. Two molecules of H3 protein
c. Two molecules of H4 protein
d. One molecule of H1 protein - answer✔d. One molecule of H1 protein
The transfer of information from parent to progeny that is not based on DNA sequences is known
as
d. Mendelian genetics. - answer✔a. epigenetic inheritance.
In the chromatin around centromeres, nucleosomes are present that have a unique structure in
which the core protein _______ is replaced by _______, and this variant of the nucleosome is
required for protein assembly at the kinetochore.
a. histone H3; CENP-A
b. histone H3; histone H5
c. histone H1; CENP-A
d. histone H1; histone H5 - answer✔a. histone H3; CENP-A
During metaphase in actively dividing cells, DNA is in
a. heterochromatin.
b. nucleoli.
c. chromosomes.
d. euchromatin. - answer✔c. chromosomes.
A centromere is a
c. region where proteins bind to form kinetochores.
d. specific, repeated DNA sequence. - answer✔c. region where proteins bind to form
kinetochores.
Heterochromatin gets its name from the fact that it contains a mixture of active and inactive
genes.
True or False - answer✔False
The function of telomeres is to
a. condense the chromosomes in preparation for mitosis.
b. ensure chromosome replication and maintenance.
c. hold the sister chromatids together and bind the spindle during mitosis.
d. provide a binding site for DNA polymerase to initiate replication. - answer✔b. ensure
chromosome replication and maintenance.
Interaction between the finger-like projections of histones with DNA is based on a charge
attraction
True or False - answer✔True
The extended length of all the DNA in one human cell is about two
d. kilometers. - answer✔c. meters.
Heterochromatin consists of
a. DNA associated with nucleosomes.
b. 10-nm chromatin fibers.
c. decondensed, transcriptionally active chromatin.
d. highly condensed, transcriptionally inactive chromatin. - answer✔d. highly condensed,
transcriptionally inactive chromatin.
During mitosis, highly condensed chromosomes consist of two sister chromatids joined at the
a. centrosome.
b. centromere.
c. kinetochore.
d. spindle fiber - answer✔b. centromere
Euchromatin consists of
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