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NURS 307 - Midterm - Genetics, Cancer and Altered Glucose Regulation Questions With Complete Solutions $17.99
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NURS 307 - Midterm - Genetics, Cancer and Altered Glucose Regulation Questions With Complete Solutions
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NURS 307 - Midterm - Genetics, Cancer and Altered Glucose Regulation Questions With Complete Solutions

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  • October 19, 2024
  • 52
  • 2024/2025
  • Exam (elaborations)
  • Unknown

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  • nurs 307 midterm genetics cancer and altered

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  • NURS 307

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NURS 307 - Midterm - Genetics, Cancer and Altered
Glucose Regulation Questions With Complete Solutions

Abiraterone CYP17 inhibitor Correct Answer - used in
metastatic castration resistant prostate cancer
- last form of treatment
- inhibits androgen production by adrenal glands and prostage
- sodium retention, loss of K, fluid retention, edema, HTN,
hypokalemia, hepatotoxicity

Acarbose Correct Answer Flatulence, cramps, abdominal
distension, diarrhea, liver dysfunction

Acute leukaemia Correct Answer - patient presents with
pantocytopenia
- symptoms of anemia, infections and bleeding
- if untreated 6-12 wks till death
- blood smear looking for immature WBCs (blast cells) and
WBCs can be high, normal or low depending on symptoms

Acute Lymphocytic Leukemia (ALL) Correct Answer - can be
B or T cell
- cells cannot differentiate
- patients present wit low RBCs, Plts, enlargement of the liver,
low neutrophils, and WBCs high or low

Acute mylogenous leukemia (AML) Correct Answer -
proliferation of bast cells that cannot differentiate
- patient presents with high WBCs, low RBCs, low neutrophils
and Plts
- disrupts retinoic acid receptor

,Adaptations Correct Answer Reversible changes in the number,
size, phenotype, metabolic activity or functions of cells in
response to changes in their environment

Adenocarcinoma Correct Answer Cancer from glandular
epithelial tissue

Adenomas Correct Answer Benign tumours arising from
glandular epithelial tissue

Adjuvant chemo Correct Answer after surgery

Alkylating agents (CCNS) Correct Answer Nitrogen mustards
Nitrosoureas
Platinum compounds

Alpha-glucosidase inhibitors Correct Answer - act in intestine
to delay absorption of carbs (inhibits A-G receptors)
- acarbose
- migitol

Altered genes leading to cancer Correct Answer Oncogenes
Tumour suppressor genes
Repair or mutator genes

Amylin mimetics Correct Answer Pramlintide (Symlin)

Anastrozole Correct Answer - causes musculoskeletal pain,
headaches, and menopausal symptoms. Nausea, vomiting and
diarrhea, hypertension, peripheral edema

,Androgen deprivation therapy Correct Answer - commonly
used in prostate cancer
- time limited because the tumour can become resistant to these
drugs

Androgen receptor blockers Correct Answer - only indicated
for advanced androgen sensitive prostate cancer in combination
with GnRH agonist
- flutamide

Aneuploidy Correct Answer the presence of an abnormal
number of chromosomes in a cell

Angiogenesis inhibitors Correct Answer - suppress formation if
new blood vessel and deprive solid tumours of expanding their
blood supply for continued growth
- does not kill cancer cells

Anthracyclines Correct Answer - severe bone marrow
depression and heart damage
- doxorubicin, daunorubicin

Anti-estrogens Correct Answer - block estrogen receptors and
only work against cells that are ER+
- tamoxifen

Anti-Metabolites (CCS-S Phase) Correct Answer - structural
analogs of natural metabolites
- folic acid analogs
- pyrimidine analogs

, - purine analogs

Anti-tumour Antibiotics (CCNS) Correct Answer - cytotoxic
drugs isolated from bacteria
- used only to treat cancer
- anthracyclines
- non-anthracyclines

Apoptosis Correct Answer - cellular condensation
- membranes remain intact
- requires ATP
- cell is phagocytoses, no tissue reaction
- ladder like DNA fragmentation
- no inflammation
- programmed cell death promoted by a genetic signal or to
replace old cells with new cells

Aromatase inhibitors + monoclonal antibodies Correct Answer
- treats ER+ cancers in POSTMENOPAUSAL women
- may cause a rise in estradiol in premenopausal women
- anatrozole, trastuzumab,

Aspart (novolog) Correct Answer - onset 15-30 mins
- SC or insulin pump
- 5-10 mins before meals

Atrophy Correct Answer Decrease in the size and function of a
cell

Autosomal dominant Correct Answer - vertical pattern
- male and female equally likely to be affected

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