NWHSU PNS - EXAM 3 Questions And
Answers
CN X will have (positive/negative) chronotropic and ionotropic effect. Negative - lower
heart rate and contractility.
A sIPSP will do what to the heart? lower rate and contractility.
Which nerve and side is primarily responsible for maintaining restin...
CN X will have (positive/negative) chronotropic and ionotropic effect. Negative - lower
heart rate and contractility.
A sIPSP will do what to the heart? lower rate and contractility.
Which nerve and side is primarily responsible for maintaining resting heart rate? Right
Vagus.
In a g-coupled receptor system, it is common for the end of the chain to activate a protein kinase
A, which causes this type of potential ______________, by doing this to the membrane
________________.
What channel needs to open for this to happen? sIPSP by phosphorylating (adding
phosphates) to the inside of the membrane.
NO CHANNEL IS NECESSARY IN THIS SPECIFIC EXAMPLE!
, NWHSU PNS - EXAM 3 Questions And
Answers
What do all slow potentials require?
Do all of these result in a membrane potential change? A second messenger is needed.
Not all 2nd messengers result in change in potential.
Epinephrine is this class of molecule: catecholamine
PK-A stands for protein kinase a
The response from PK-A is (+ or -) +++ excitatory
Beta 1 (________) receptors do what? They are mostly in this spot: (adrenergic)
increase heart rate, mostly on the AV node.
The AV is dominated by _______ effect
The SA node is dominated by _________ effect.
, NWHSU PNS - EXAM 3 Questions And
Answers
Choose autonomic response. The AV is dominated by __sympathetic__ effect
The SA node is dominated by ____parasympathetic_____ effect.
(T/F)
All 2nd messengers result in slow potentials False. A b-1 receptor causes contraction, for
example by acting INTRAcellularly.
Main examples of 2nd messenger systems causing:
sIPSP
sEPSP sIPSP - M2
sEPSP - Substance P
Other than potentials, what can 2nd messengers do? Intracellular processes like
contractions, DNA expression, gene regulation, and extracellular processes like inflammation
Angiotensin is released by the kidney
, NWHSU PNS - EXAM 3 Questions And
Answers
Angiotensin II vasoconstrictor
What system works to cause vasoconstriction, and what channels need to open, and what ions
move across the membrane? With Ang II, a second messenger is used to work
intracellularly, so no channels open, no ions flow in/out.
Are GABAb receptors going to use a 2nd messenger?
As a reminder, what type of potential results? Yep, they trigger cAMP to do it's thing.
sIPSP
what might cAMP do in this system from GABAb? open channel for K+ and Ca++ OUT
of cell to cause sIPSP
Reuptake of GABA via _____ cells.
GABA breaks down to ______ then _______. This process reverses and makes GABA again.
glial
GABA->glutamate->glutamine->glutamate->GABA
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