MAA Particle size - answer90% between 10-90 microns, no more than 150
Particle size for unfiltered SC - answerless than 1 micron
Particle size for filtered SC - answer0.22 microns
Where does SC when particles are too large - answer Lungs
Where does Mo99m go when there is too much in eluate (>0.15 microcurie/1 mCi Tc) -
answer Liver (parenchymal cells)
Where will you see alumina uptake? - answer Liver on a bone scan (>10 micrograms/ml
of Tc eluate)
Where will you see MAA go when the particles are too small? - answer Kidneys, brain,
maybe liver
Where would you see uptake of FREE Tc99m? - answer thyroid, stomach, salivary
glands, choroid plexus
Where would you see uptake of REDUCED HYDROLYZED Tc99m? - answercolloidal
particles localize in the liver
What is the purity percentage for Pertechnetate - answer>95%
What is the purity percentage for most Tc kits? - answer>90%
What is the purity percentage for SC? - answer>92%
What is the conversion for MBq to mCi? - answer37 MBq = 1 mCi
What is the conversion for kg to lbs? - answer2.2 lbs = 1 kg
What regulatory guidelines are the DOT under for radiation safety? - answerTitle 49
CFR 171-173
What regulatory guidelines are the NRC under for radiation safety? - answerTitle 10
CFR part 19, 20, 30, 31, 32, 33, 35, 71 (DOT)
What is the equation for Total dose? - answertotal dose = (dose rate)(time)
, How are HVLs incorporated into the total dose equation? - answer2 HVLs: total dose =
(dose rate * 0.5 * 0.5)(time)
Ra 223 (Xofigo) - what form of radiation and what is its purpose? - answeralpha
radiation and treatment of CSPC (castration specific prostate cancer) - 1.35 uCi/kg
I-131 - what form of radiation and what is its purpose? - answerGamma,Beta and
treatment for hyperthyroidism, thyroid cancer, NHL -
Sr-89 (Metastron) - what form of radiation and what is its purpose? - answerBeta and
treatment of bone pain - 40 to 60 uCi/kg
Sm-153 EDTMP (Quadramet) - what form of radiation and what is its purpose? -
answerGamma,Beta and treatment of bone pain - 1 mCi/kg
*Gamma (103 keV) is for imaging and Beta is for therapy*
I-125 seeds - what form of radiation and what is its purpose? - answerGamma and
brachytherapy - implanted into the prostate gland using US guidance
Y-90 - what form of radiation and what is its purpose? - answerBeta,Xray and treatment
of NHL (Zevalin) or Hepatic metastasis (microspheres/theraspheres)
*Zevalin - 0.3 to 0.4 mCi/kg (max 32 mCi)*
*Therasperes - 35 to 70 mCi intra-arterial*
What are anticoagulant options? - answerACD (for RBC labeling) , EDTA (for GFR Tc
tagging), or Heparin (for PICC lines or ports)
Image evaluation: what is happening when you see vascularity (vascular structures) on
a RBC study? - answerThere is some sort of RBC issue - minimal liver/spleen, more
veins/arteries
Image evaluation: hot liver/spleen - answerSC localizes here
Image evaluation: stomach activity and RLQ activity if abnormal - answerMeckels
Image evaluation: In-111 WBC or Tc99m HMPAO? - answerBladder on HMPAO
because IN-111 isnt excreted through the bladder
Steps for labeling WBCs with In-111 - answer1. Collect cells in 60cc syringe with ACD
2. let cells settle
3. draw off wbc rich plasma and centrifuge (discard RBCs)
4. draw off *platelet rich plasma (PRP)* and added In-111 to WBC button
5. centrifuge PRP - draw off *platelet poor plasma (PPP)*
6. re-suspend wbcs in PPP and reinject into patient
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