What is the normal glucose level? What indicates hypoglycemia? What indicates
hyperglycemia?
7-100 mg/dL. Under 70. Over 100
What a C-peptide a precursor to? - ANSWER insulin
What are the core defects of diabetes? - ANSWER insulin resistance
impaired insulin secretion
increased hepatic glucose production
accelerate lipolysis in fat cells
incretin resistance/ deficiency in the duodenum
hyperglycagonemia
increased glucose absorption by the kidney
insulin resistance in the brain
What cells are destroyed in type 1 diabetes? - ANSWER Beta cells of the islets of
Langerhans
What are the risk factors for type 1 diabetes? - ANSWER autoimmune
virus exposure
What are the clinical manifestions of type 1 diabetes? - ANSWER polyuria
polydipsia
polyphagia
, What is the pathophysiology of type 2 diabetes? - ANSWER insulin resistance
What are the risk factors for type 2 diabetes? - ANSWER family history
obesity
elderly
What are the clinical manifestations of type 2 diabetes? - ANSWER fatigue
recurrent infections
hypoglycemia means blood glucose is less than ___. - ANSWER 70
What are the risk factors for hypoglycemia? - ANSWER too much insulin
not eating
exercise
ETOH
What are the clinical manifestions of hypoglycemia? - ANSWER tachycardia
irritability
restless
excessive hunger
diaphoresis
How is diabetes diagnosed? - ANSWER Fasting blood sugar
Oral glucose tolerance test (OGTT)
random
HgbA1C (glycosylated hemoglobin)
C-peptide
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