NUR 213 Test 3
1. Contraindications for Antirejection Immunosuppressants
Answer
Active infections, lymphoma
Pregnancy, breastfeeding Concomitant vaccine administration Renal or hepatic impairment
2. Tacrolimus and Sirolimus boxed warning
Answer
infants and children, clients under- going liver transplant
3. Cyclosporine boxed warning
Answer
systemic hypertension and nephrotoxicity
4. Live attenuated vaccines
Answer
- Contain pathogen that have been weakened in the laboratory
- No longer able to cause infection
- Still able to trigger protective immune response
5. Inactivated vaccines
Answer
- Use a pathogen that has been killed in the laboratory
- No longer able to replicate or cause infection
- Still able to trigger a protective immune response
6. Subunit, recombinant, and polysaccharide vaccines
Answer
Contain just the portion of pathogen that stimulates the immune response
7. Conjugated Vaccines
Answer
Stronger and longer lasting immune response
8. Toxoid vaccines
Answer
Inactivated toxins produced by pathogens protect against tetanus and diphtheria
9. mRNA Vaccines
Answer
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,- Codes for a harmless viral protein
- Unable to cause disease
- Capable of triggering an immune response
10. First generation antihistamines (examples)
Answer
- can more easily cross the blood brain barrier
- Lethargic, can sedate
13. second generation antihistamines
Answer
better for use during the day
14. indications for first generation antihistamines
Answer
Allergic rhinitis Allergic conjunctivitis
Urticaria Anaphylaxis
Common cold Nausea and vomiting Motion sickness Insomnia
15. Indications for second generation antihistamines
Answer
Allergic rhinitis Allergic conjunctivitis
Urticaria Anaphylaxis Common cold
16. example of methylxanthines
Answer
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, theophylline
17. mechanism of action of theophylline
Answer
Enters smooth muscles of the airways and inhibits the enzyme phosphodiesterase, leading to
smooth muscle relaxation
18. Theophylline
Answer
Can be used in asthma and COPD Bronchial smooth muscle relaxation
Dilation of the narrowed airways and improved air flow
19. Bronchodilators
Answer
theophylline is a
20. Mechanism of Biologic Agents -
TNF Blockers (etanercept (Enbrel), infliximab (Remicade, Renflexis,
Avsola, Inflectra), adalimumab (Humira))
Answer
Prevent TNF from attaching to its re- ceptor ’ suppress immune response
21. Mechanism of Biologic Agents - IL-1 inhibitor, IL-6 inhibitor, IL-17A in- hibitor (anakinra
(Kineret)
tocilizumab (Actemra, Actemra ACTPen)
secukinumab (Cosentyx, Cosentyx Sensoready Pen))
Answer
Prevent IL-1, IL-6, or IL-17A from attaching to their receptors ’ suppress immune response
22. Nursing considerations for inhalers
Answer
Shake mdi canister Exhale all air out of the lungs
Put spacer mouthpiece to mouth, make tight seal Press down in mda
Inhale slowly and deeply, hold breath for 5-10 seconds then fully exhale If needs more than 1
puff, wait 1 min before 2nd puff
Gargle and rinse the mouth to decrease thrust
23. Spacer
Answer
Promotes maximal delivery of medication to lungs
24. Nursing Considerations for nasal decongestants
Answer
Assess nasal passages before administration
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