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NU578 - Unit 1/NU 578 Unit 1 Test With Latest 100%Correct Answers./ UPDATE !!
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10/21/24, 1:28 PM NU578 - Unit 1/NU 578 Unit 1 Test With Latest 100%Correct Answers./2024-2025 UPDATE !! Flashcards | QuizletNU578 - Unit 1/NU 578 Unit 1 Test With Latest
100%Correct Answers./2024-2025 UPDATE !!
Terms in this set (160)
Drugs in this schedule have no accepted medical
use in the United States and have a high abuse
Schedule I potential.
Examples are heroin, marijuana, LSD, peyote, etc.
Drugs in this schedule have a high abuse potential
with severe psychic or physical dependence liability.
Included are certain narcotic analgesics, stimulants,
and depressant drugs.
Schedule II Examples are opium, morphine, codeine,
hydromorphone, methadone, meperidine,
oxycodone, anileridine, cocaine, amphetamine,
methamphetamine, phenmetrazine,
methylphenidate, amobarbital, pentobarbital,
secobarbital, methaqualone, and phencyclidine.
Drugs in this schedule have an abuse potential less
than those in Schedules I and II and include
compounds containing limited quantities of certain
narcotic analgesic drugs, and other drugs such as
barbiturates, glutethimide, methyprylon, and
Schedule III
chlorphentemine.
Any suppository dosage form containing
amobarbital, secobarbital, or pentobarbital is in this
schedule.
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, 10/21/24, 1:28 PM NU578 - Unit 1/NU 578 Unit 1 Test With Latest 100%Correct Answers./2024-2025 UPDATE !! Flashcards | Quizlet
Drugs in this schedule have an abuse potential less
than those listed in Schedule III and include such
drugs as barbital, phenobarbital, chloral hydrate,
Schedule IV
ethchlorvynol, meprobabmate, chlordizepoxide,
diazepam, oxazepam, chloroazepate, flurazepam,
etc.
Drugs in this schedule have an abuse potential less
than those listed in Schedule IV and consist
Schedule V primarily of preparations containing limited
quantities of certain narcotic analgesic drugs used
for antitussive and antidiarrheal purposes.
Process of drug movement from its site of
Absorption
administration into the blood
Most common passive diffusion
mechanism for drug
absorption
Rapid hepatic inactivation of certain oral drugs
First-pass effect
(presystemic metabolism) drug is metabolized (chemically altered) as it passes
through either 1) gut wall, and 2) liver.
drug movement from the blood to the interstitial
Distribution
space of tissues and from there into cells
- Blood brain barrier
Barriers to distribution
- Placenta
- Perfusion
Physiologic Factors
- Binding of drug to plasma protein
Affecting Distribution
- Specialized Distribution Barriers
Albumin Binds acidic drugs
Prevents bound drug molecules from leaving the
bloodstream
Protein (albumin) binding
Prolongs the distribution phase (Increases half-life)
alpha-1 acid glycoprotein Binds basic drugs
Reservoir effect
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