Which justification would an IACUC most likely accept if a research team plans to withhold
pain relief (analgesia) from animals during a project? Correct Ans-Documented evidence
that the analgesic agent will interfere with the aims of the project.
Prior to implementing any significant change in the use of animals, what is the most
important thing that the research team must do? Correct Ans-Obtain IACUC approval for
the change.
Which of the following most clearly illustrates Russell and Burch's Replacement concept?
Correct Ans-The use of computer modeling software instead of using animals in an
experiment.
What is the primary purpose of the "3Rs" concept from Russell and Burch? Correct Ans-To
decrease the use of animals in research and to minimize pain and distress caused by animal
experiments.
Which of the following most accurately describes the process that must occur when working
with research animals covered by U.S. federal regulations? Correct Ans-The research team
must obtain IACUC approval for the proposed research procedures prior to starting the work.
Which of the following is true regarding the use of animals in research? Correct Ans-The
attending veterinarian must be allowed to have access to all research animals at all times.
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