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NURS 5315 UTA EXAM 2 QUESTIONS AND ANSWERS 2024

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NURS 5315 UTA EXAM 2 QUESTIONS AND ANSWERS 2024

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  • October 21, 2024
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NURS 5315 UTA EXAM 2

causes of thrombus - ANSWERS-Triad of Virchow- injury to blood vessels,
abnormality in blood flow, hypercoagulability

some medications increase risks



discuss macrocytic, microcytic, and normocytic anemias - ANSWERS-classified by
size of RBC

macrolytic- MCV >100, includes pernicious and folic acid anemias, can be caused
by ETOH

microlytic- MCV <80, folic acid anemia

normolytic- MCV 80-100 (normal range), sickle cell is an example



Pathophysiology and clinical implications of pernicious anemia - ANSWERS-A
Vitamin B12 deficient leads to fewer RBCs- intrinsic factor is lacking- RBCs get big,
but not mature

Macrocytic

Typical at age 60 as 10 years of B12 is stored in body



Risk factors and CM of pernicious anemia - ANSWERS-Risk: vegan, gastrectomy,
atrophy of gastric mucosa r/t autoimmune disease

CM: beefy red tongue, weakness, fatigue, loss of appetite, weight loss,
neurological symptoms- parenthesis of hands/feet, loss of sense of position and
vibration

,Pathophysiology and clinical implications of folate deficient anemia - ANSWERS-
Folic acid is required for RBC synthesis, when lacking, cell continues to grow- but
not mature, will get large and be destroyed in the bone marrow

Monitor nutritional status of patients, elderly are easily malnourished

ETOH dependent may need supplementation



Risk factors and CM of folate deficient anemia - ANSWERS-Risk: malnourished,
alcoholic

CM: beefy red tongue, weakness, fatigue, loss of appetite, weight loss



Risk factors and CM of iron deficient anemia - ANSWERS-Risk: PUD, excessive
menstruation, occult GI bleed, inadequate dietary intake, Meds with GI bleed risk

CM: fatigue, hypoxia, SOB, pale tissues, glossitis, spoon shaped nails



Pathophysiology and clinical implications of iron deficient anemia - ANSWERS-
Microcytic

Iron is necessary for production of hgb. Iron stores are depleted and less hgb is
produced, results in small RBCs

Most common worldwide, usially from chronic blood loss or pregnancy, more
common in women



Risk factors and CM of anemia of chronic disease - ANSWERS-AIDS, RA, CKD,
chronic hepatitis, lupus

, 2nd most common, chronic disease leads to body's inability to use iron stores



Risk factors and CM of sickle cell anemia - ANSWERS-African descent,
Mediterranean, middle eastern, or Indian descent, familial history

Pain during crisis



Pathophysiology and clinical implications of sickle cell anemia - ANSWERS-Lack of
O2 causes hgb S molecules to transform to sickle shape, treat with 0.45% NaCl to
rehydrate cell and reverse shape change

Autosomal recessive- can carry trait or active form.



Define acute leukemia - ANSWERS-Rapid onset- aggressive accumulation of
immature cells, causes overproduction of leukocytes by the bone marrow, causes
overcrowding, prevents formation of normal blood cells



Chronic leukemia - ANSWERS-Gradual onset, cells appear normal but do not
function appropriately and accumulate



Lymphocytic leukemia - ANSWERS-Excessive production of lymphocytes



Myelogenous leukemia - ANSWERS-Excessive production of granulocytes



Multiple myeloma pathophysiology and CM - ANSWERS-Chromosomal
abnormality that leads to production of malignant plasma cells, cells secrete

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