Answer
elevated BP is
4. SBP of 180 or more and/or DBP over 120 or higher
Answer
BP for a hypertensive crisisi is1
5. CO, preload, afterload, contractilty
Answer
determinants of BP
6. cardiac output
Answer
the total volume of blood ejected from the heart per minute (4-6 L/min); aka systolic pressure.
7. stroke volume
Answer
The amount of blood ejected from the heart in one contraction (60-130 ml)
* impacted by preload, afterload, contractility
8. preload
Answer
volume of blood in ventricles at end of diastole
9. afterload
Answer
Resistance to ejection of blood from the ventricle.
10. systemic vascular resistance
,Answer
resistance to blood flow out of the left ventricle created by the systemic circulatory system; aka
diastolic pressure.
11. contractility
Answer
Force generated by the contracting myocardium.
Enhanced by circulating catecholamines, sympathetic neuronal activity, and certain medications.
12. beta 1 receptors
Answer
increase heart rate and contractility
13. beta 2 receptors
Answer
help stimulate the RAAS system in the kidney
15. Rening Angiotensin-aldosterone system
Answer
- decreased perfusion to the affer- ent renal artery causes renin release
- combines with angiotensinogen to form angiotensin 1
- ACE converts ang. 1 to ang. 2
- vasoconstriction occurs
- aldosterone is released to increase na/water retention and blood volume
- blood pressure increases
16. epinephrine and norepinephrine
Answer
Neurotransmitters secreted by the adrenal medulla in response to stress..increases HR and BP.
17. first line interventions for HTN
Answer
- captopril (prototype), other "-prils"
- Action
Answer
Prevents conversion of angiotesin I to ang. II. Lowers BP with little change to CO or HR
-Indications
Answer
not for use during pregnancy
- contraindications
Answer
K+ sparing diuretics (spironolactone), salt substitutes w/K+
-Other
Answer
take captopril 1 hr before food. Increases Lithium and digoxin concentrations. Does not work as
well when used alone in African Americans and older adults.
19. angiotensin 2 receptor blockers
Answer
- lorsartan, other "-sartans", o. medoxomil
- Action
Answer
blocks vasoconstrictive effects of angiotensin II at the receptors in vascular smooth muscle and
increases renal blood flow; decreases BP.
- Indications
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