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MCT NBME Review Questions and Answers
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MCT NBME Review Questions and Answers B - Ans:-(Marks' Medical Biochemistry Chapter 5) A patient was diagnosed with one of the types of sphingolipidoses, which are congenital diseases involving the ability to degrade sphingolipids. All sphingolipids have in common which one of the following? A...

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  • October 22, 2024
  • 103
  • 2024/2025
  • Exam (elaborations)
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FIRST PUBLISH OCTOBER 2024




MCT NBME Review Questions and Answers



B - Ans:✔✔-(Marks' Medical Biochemistry Chapter 5)


A patient was diagnosed with one of the types of sphingolipidoses, which are congenital diseases

involving the ability to degrade sphingolipids. All sphingolipids have in common which one of the

following?


A. a glycerol backbone


B. ceramide


C. phosphorylcholine


D. N-acetylneuraminic acid (NANA)


B - Ans:✔✔-(Marks' Medical Biochemistry Chapter 6)


Protein kinases phosphorylate proteins only at certain hydroxyl groups on amino acid side chains. Which

of the following groups of amino acids all contain side-chain hydroxyl groups?


A. aspartate, glutamate, serine


B. serine, threonine, tyrosine



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C. lysine, arginine, proline


D. alanine, asparagine, serine


A - Ans:✔✔-(Marks' Medical Biochemistry Chapter 13, #5)


Autopsies of patients with Alzheimer disease show protein aggregates called neurofibrillary tangles and

neuritic plaques in various regions of the brain. These plaques exhibit the characteristic staining of

amyloid. Which of the following structural features is the most likely characteristic of at least one protein

in these plaques?


A. a high content of beta-pleated sheet structure


B. a high content of alpha-helical structure


C. a high content of random coils


D. disulfide bond cross-links between polypeptide chains


B - Ans:✔✔-(Marks' Medical Biochemistry Chapter 13, #5)


The key mechanistic failure in patients with xeroderma pigmentosum involves which of the following?


A. Mutation in the primase gene


B. Inability to excise a section of the UV-damaged DNA




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C. Mutation of one of the mismatch repair components


D. Inability to synthesize DNA across the damaged region


E. Loss of proofreading capacity


C - Ans:✔✔-(Marks' Medical Biochemistry Chapter 30, #3)


A newborn is diagnosed with neonatal jaundice. In this patient, the bilirubin produced lacks which of the

following carbohydrates?


A. glucose


B. fructose


C. glucuronate


D. galactose


E. galactitol


D - Ans:✔✔-(Marks' Medical Biochemistry Chapter 31, #1)


A common intermediate in the conversion of glycerol and lactate to glucose is which of the following?


A. pyruvate


B. oxaloacetate

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C. malate


D. glucose-6-phosphate


E. phosphoenolpyruvate


A - Ans:✔✔-(Marks' Medical Biochemistry Chapter 31, #2)


A patient presented with a bacterial infection that produced an endotoxin that inhibits

phosphoenolpyruvate carboxykinase (PEPCK). In this patient, then, under these conditions, glucose

production from which of the following precursors would be inhibited?


A. alanine


B. glycerol


C. even-chain fatty acids


D. phosphoenolpyruvate


E. galactose


C - Ans:✔✔-(Marks' Medical Biochemistry Chapter 31, #3)


Which of the following statements best describes glucagon?


A. It acts as an anabolic hormone.


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