NR 507 MIDTERM EXAM 2 / NR 507 WEEK 4
ADVANCED PATHOPHYSIOLOGY MIDTERM
EXAM|| LATEST 2024-2025 UPDATE WITH ALL
QUESTIONS AND 100% CORRECT ANSWER
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Examples of hypersensitivity type 1 - ANSWER: allergic rhinitis, anaphylactic
reaction
Type 1 hypersensitivity reactions are mediated by what - ANSWER: IgE
What cells are involved in hypersensitivity type 1 - ANSWER: Mast cells
symptoms of hypersensitivity type 1 - ANSWER: local: itching, immediate rash
systemic: wheezing
main treatment for anaphylaxis - ANSWER: epinephrine
Type 2 hypersensitivity is also known as what kind of reaction? - ANSWER:
cytoctoxic reaction, tissue specific
what cells are involved in type 2 hypersensitivity reaction? - ANSWER:
Macrophages
what does type 2 hypersensitivity do to tissues? - ANSWER: can cause damage or
alter function of specific tissues
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Examples of hypersensitivity type 2 - ANSWER: graves disease/ hyperthyroidism,
blood incompatibility
what is the difference between type 2 and 3 hypersensitivity? - ANSWER: type 2
is organ specific; antibody binds to the antigen on the surface of the cell
type 3 is NOT organ specific; binds outside of the cell surface and is released into
blood/ body fluids and then deposited into tissues
examples of type 3 hypersensitivity - ANSWER: rheumatoid arthritis and lupus
autoimmune diseases can be... - ANSWER: genetic/familial
What is alloimmunity? - ANSWER: Immune reaction to tissues of another
individual
what is hypersensitivity type 4 - ANSWER: Delayed response, Occurs 24-72 hrs
after exposure
doe not involve antigen/antibody complexes
Hypersensitivity type 4 is mediated by what? - ANSWER: T cells!!!
example of hypersensitivity type 4 - ANSWER: contact dermatitis
poison ivy
delayed response occurs in area of contact
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