Research that takes place in labs or non labs, goal is to provide direct solutions to
practical problems.
Clinical
Research that has little clinical application, takes place in carefully controlled lab.
Basic
Difference in strength of evidence comes from 2 sources???
Sampling and research method
A ________ sample is more likely to estimate true population values and result in
narrower confidence intervals.
Large
Hierarchy of evidence - list best to worst types of research
, Systematic reviews (of meta-analyses), Randomized, non-randomized, case studies
(series, surveys), animal, in-vitro research
A report of the presentation, treatment and outcome of a patient (case study) or group
of patients (case series).
Important to inform research
Case Study
Inexpensive, Can collect data regarding the prevalence of disease and trends in health
care
Good precurser for planning and designing experimental studies
Survey
Case control and cohort studies, Observations of patients w/out controlling variables.
Often records are reviewed. May be retrospective or prospective
Non-randomized observational study
retrospective design. Begin with individuals who have a disease and compare with
appropriate controls, those who do not have the disease. Question regarding exposure.
Good for : rare conditions, studies that are ethically difficult to perform, inexpensive
Case Control study
retrospective or prospective. A cohort is a group of people who share some common
experience in a defined time period.
Good when exposure and disease is well recorded
Cohort studies
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