Interstitial fluid = 3/4 of ECF Large amounts of Na and CL
Small amounts of K, Mg, Ca, phosphate
3. Diffusion
Answer
Movement of solutes from area of higher concentration to lower con- centration
Restores balance by redistribution of electrolytes
4. Osmosis
Answer
Movement of water from area of more water to less water.
Fewer solutes to more solutes.
Moves water through semi-permeable cell membrane
5. Active transport
Answer
Movement of solutes from area of lower concentration to higher concentration -- requires energy
6. Osmolality
,Answer
Osmolar concentration in 1kg of water
Determined by sodium. Na pulls water with it. If sodium level goes up, osmolality level goes up.
7. Tonicity
Answer
Tension or effect that osmotic pressure of solution with impermeable solutes exerts on cell size
because H2O movement across the cell membrane.
8. Isotonic
Answer
Same osmolality as body fluids. Fluid doesnt move in or out of cell.
Cell size doesnt change
9. Hypotonic
Answer
Less concentrated inside the cell.
Fluids move INTO the cell from the blood. Cells swell.
10. Hypertonic
Answer
More concentrated inside the cell.
Fluids move OUT of the cell into the blood. Cells shrink. Poor skin turgor.
-Pressure pushing water out of capillary into interstitial spaces
- High BP = high capillary filtration pressure (Pushes more fluid out)
- Low BP = low capillary filtration pressure
, 12. Interstitial hydrostatic pressure
Answer
Opposes movement of water out of capillary
-Maintains the movement
- Normally negative
13. Capillary colloidal osmotic pressure
Answer
Colloid = protein
Proteins are too large to pass thru pores/semi-permeable membrane of capillary wall. So they
create their own pressure (osmotic) and just stay put.
They pull water too them and into the capillary
14. What condition would cause decreased capillary colloidal osmotic pres- sure?
Answer
Malnutrition bc not getting adequate # of proteins
Liver disease bc a lot of proteins in liver
Kidney disease bc kidneys release proteins into the urine
15. Tissue colloidal osmotic pressure
Answer
Pulls water out of capillary into interstitial spaces
16. What condition would increase capillary filtration pressure?
Answer
Edema Hypertension
Congestive Heart failure
CFP increased by increase in venous pressure & capillary distention caused by increased
vascular volume
17. What are the determinants of fluid shifts between the ICF and ECF?
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