WGUlD441lFinallExamlGuidel(Latestl
Update)lMedicallDosagelCalculationslandl
Pharmacology |Qsl&lAs|l100%lCorrect|l
GradelAl(VerifiedlAnswers)
Q:lCarbamazepinelnursinglconsiderations
Answer:
l1.Monitorlintakelandloutput
2.Superviselambulation
3.Monitorlcompletelbloodlcount
Q:lCarbamezapinelboxedlwarning
Answer:
lSJS,lTENl(Toxiclepidermallnecrolysis)lbonelmarrowlsuppression
-avoidlgrapefruit
-ls/sloflwaterlretentionlandlhyponatremia
-lnervelpainl2/2lagranulocytosis=ldecreasedlWBC
Q:lValporiclAcidlspeciallconsiderations
Answer:
lCI:lOB,lurealcycleldisorders,lhepaticldisease.
-ldecreaseslCNS;ltakelatlnightltolavoidlinjury
Q:lDopaminergic
Answer:
lName:lCarbidopa-Levodopa
Use:lParkinsons
,Responsibilities:lVS,lBP!lCBC,lLFT,lProlactin,lHCGlScreen:lgaitltremorslposture
SI:lcaridiacldysrhythmias,lthrombocytopenia,lagranulocytosis,lurinarylretention
l
CI:lGlaucoma,lmalignantlmelanoma
-lanticholinergic/antisych:ldecreaseleffect
MAO:lHTN,ltriggerslmelanomalprotein:ldecreaseslabslTyramine:lHTN
Edu:ldolnotlcrush
-darklurinelislnormal
-reportldyskenesia
-llowlproteinldiet
-lavoidltyraminelfoods:lredlwine,lyogurt,lbanana,lagedlcheese
Q:lAntiparkinsonianldrugs
Answer:
lMedicationslusedlinltheltreatmentloflParkinson'sldiseaseltolrelievelsymptomslandlmaintainlmo
bility,lbutldolnotlcureltheldisease
Dopaminergic:lcarbidopa-levodopa
DopaminelAgonists:lamantadine,lbromocriptine,lpramipexole,lropinirolelHCLlMonamineloxida
se-lBlinhibitorsl(MAO):lSeleglinelHCL,lrasagiline
Catechol-o-methylltransferasel(COMT)linhibitors:lentacopaone,lTolcapone
Anticholinergics:lTrihexyphenidyl,lbenztropine,lbiperiden
Q:lAcetylcholinesteraselinhibitors
Answer:
lName:lRivastigmine
-ltacrine,ldonezepil
Use:lAlzheimers,ldoeslnotlcure
Responsibilities:lAmbulatorylassistance,lBP,lHRlLFT
SI:lincreasedlsalivation,lRespiratorylDepression,lSI,lSJS,lHepatotoxicity,lMI/HF
CI:lHypersensitivityltolcarbamatelderivatives
-theophylline:lincreasesldrugllevel
-TCA:ldecreaseleffectloflrivastigmine
-Cimetidine,lGinko:lincreasesleffectloflriv
-tobacco;lincreaseslclearance
l
Edu:ltakelwithlfood,lsafetyltechniques,lsupportlgroups
Reportlimmediately:lsevereln/vlandlincreasedlsalivation
,Q:lTCA's-lTricycliclantidepressants
Answer:
lName:lAmitriptylinelclormiprane,limipramine,lprotriptalyne,ldoxepin
Use:lmajorldepression,lneurologiclpain,linsomnia,leatingldisorders,lOCDlResponisibility:
observelmentallstatus
ECG
SE:lsedation,lortholhypertension,lSerotoninlsyndrome,lthirst
-BlacklBox:lSIlinlpeds,lyoundladults,ladolescents
CI:ladminsitrationloflMAOI'slwithinl14ldays
Edu:ltakelatlnight,lslowlpositionlchanges,lsugarlfeelgum
Q:lSSRIs-lselectivelserotoninlreuptakelinhibitors
Answer:
lName:lSetralinelfluoxetine,lparoxetine,lcitalopram,lescitalopram
Use:lDepression,lanxiety,lOCD,lPanic,lphobia,lPTSD,ldruglabuse,leatingldisorders
Responisibility:lVS,lmonitorlforlserotoninlsyndrome,lplateletlaggregation:lincreasedlrisklforlble
eding
-BlacklBox:lSI-
CI:lacutelanglelclosurelglaucoma
-aspirin,lnsaids,lantiplatelets,lwarfarin:lincreasedlrisklforlbleeding
-lMAOI,lOBl3rdltrimester
-Pimozide:lQTlprolongationlandlventricularlarrythmia
Edu:l4lwkslforlresponse
SE:lsexualldysfunction,lwtlgain,lAdverse:lseratoninlsyndrome
Q:lSeratoninlsyndromelsymptoms
Answer:
l-lThinklHARM
-lHyperthermia
-lAutonomiclinstabilityl(ANS)
-lRigidity
-lMentallstatuslchangel(delirium)
, l
Q:lSNRI-serotoninlandlnorepinephrinelreuptakelinhibitors
Answer:
lName:lDuloxetinelvenlafaxine,ldesvenlafixine
Use:lDepression,lAnxiety,lsociallanxietylResponsibility:lmonitorlforlserotoninlsyndrome,lSE:lin
somnia,lvisualldisturbances,lnausea
rare:lSJS,lhepaticlfailure
CI:lLinezolidl%lIVlmethylenelblue
-lanticoag,lNSAID,lslicylate
-alcohol:lincreaseslALT,lBili
-stljohnslwort:lserotoninlsyndrome
Edu:ltakesl4lweeksltolseeleffects
Q:lAtypicallAntidepressants
Answer:
lName;lbuproprion,lmirtazipine
Use:lMajorldepression,lreactiveldepression,lanxiety,lsleep,lsmoking,lResponsibility:lECGl(QRS
lprolongation),lpositionlchanges/falllprec.,lmentallstatuslSE:lSeizures,lQRSlprolongation,lSJS
CI:lheadltrauma,lstroke,lseizure
-lbupropionltox:lritonavirl&lcimetidine
-Tamoxifen,lcarbamazepine,lphenobarb,lphenytoin:ldecreasedlefficacy
-MAOI
Edu:l2wkslforlrelief:l8-14wkslforlfullleffect
-lavoidlalcohollandlotherlCNSldepressants
-ltakelwithlfoodlreportldysrrhythmias
Q:lMonoaminelOxidaselInhibitorsl(MAOIs)
Answer:
lName:lSeleglinelisocarboxid,lphenlzine,lselegline,ltranylcypromine
Use:latypicalldepression,lparkinsons
Responsibility:lVS,lBP,lmonitorlSIltendancies
Hepatic/renallfunction
