©GRACEAMELIA 2024/2025 ACADEMIC YEAR. ALL RIGHTS RESERVED
FIRST PUBLISH OCTOBER 2024
Pharm SCNM Exam Study Guide with
Complete Solutions
This is the Drug of choice for TB. it works by inhibiting synthesis of lipids or nucleic acids - Ans:✔✔-
isoniazid
(Note- Toxicity/SE: Rash, fever, jaundice and peripheral neuritis, phenytoin, age-related hepatic
dysfunction)
This drug inhibits RNA polymerase of mycobacteria
and has side effects of Orange-red urine, feces, saliva, tears, sweat; Rash, fever, Nausea and vomiting,
Jaundice and hepatitis - Ans:✔✔-rifampin
This synthetic antibiotic inhibits protein synthesis and is indicated the treatment of serious infections
that are highly resistant (e.g MRSA) - Ans:✔✔-linezolide
This antibacterial drug used to treat leprosy and some kinds of skin diseases - Ans:✔✔-Dapsone (it is a
Sulfone, SE: hemolysis)
This oral or topical antifungal is for GI/skin Tyeast only. - Ans:✔✔-Nystatin
(SE: GI Sx and rash, hypersensitivity rare, not absorbed, so more GI effects)
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Broad spectrum antifungal (systemic) that can cause Side effects involving GI, CNS, rash, hepatotoxicity,
significant drug interactions, N/V up to 10%, decrease testosterone, gynecomastia, alopecia, menstrual
irreg, at high doses decrease cortisol synthesis. - Ans:✔✔-Ketoconazole
(CI: with antacids/cimetidine, fatal terfenadine/coumadin interaction)
This antifungal is for is the Chronic use in HIV for coccidiomycosis, candidiasis and other fungi - Ans:✔✔-
Fluconazole
(CI: renal dysfunction, reactions with warfarin and more
SE: GI, CNS, rash, hepatotoxicity, significant drug interactions)
This is an Antiparasitic (OK in pediact use), for recurrent non-gonococcal urethritis trepomoniasis,
trichomoniasis, bacterial vaginosis.
C/I in first trimester
DOC in giardia - Ans:✔✔-Metronidazole
(SE: HA, nausea, dysgeusia)
This an antihelminthic drug for worms - Ans:✔✔-Albendazole
note: pediatric use OK
Acycovir - Treat? MOA? SE? - Ans:✔✔-HSV, Shingles treatment
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guanine analog
SE: NVD, Myalgia
What drug is a produg to acyclovir? What does it Treat? SE? - Ans:✔✔-Valacyclovir, to HSV
SE: HA, nausea, abdominal pain, dysmenorrhea, depression
Adefovir - Treats? SE? - Ans:✔✔-Anti-hepatitis B
Few SE: HA, rash, GI upset, increased LFT, possible nephrotoxicity
This is a cytidine nucleoside analog that treats Hep B? - Ans:✔✔-Lamivudine
effective in combination with zidovudine in treating AIDS and HIV
Inhibits HIV RevTrans and HB DNA polymerase
What anti-viral is used to treat hep B and many other DNA/RNA viruses, but is Pregnancy X? What are its
other SE? - Ans:✔✔-Ribavirin (interfeuron-alpha)
SE: CNS, GI, fever, dermatologic, flu-like sx
CI pregnancy for 6 months post-treatment
Note: also used to treat HBV + HCV
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These drugs treat viral influenza - Ans:✔✔-Amantadine, rimantadine, oseltamavir, zanamavir
These drugs are antiviral and antiparkinson's agents. Treats? SE? - Ans:✔✔-Influenza A only
SE: CNS (drowsiness, HA, dizziness, insomnia), GI (ANV, dry mouth, constipation), Anti-muscarinic
(urinary retention, orthostasis), renal toxic
NOTE: Rimantadine has less SE as amantadine
What oral treatments of influenza inhibits neuraminidase and thus assembly/release of virions? Treats?
SE? - Ans:✔✔-Oseltamavir & Zanamavir
Tx: Swine/avian flu, Influenza A & B
SE: insomnia, vertigo, NV (Zanamavir has respiratory sx because it is inhaled)
Protease Inhibitors treat HIV. What are their Side effects? - Ans:✔✔-Note: they are BAD so start low dose
and titrate up
GI upset, parathesia, rash, hyperglycemia endocrine/liver/lipid abnormalities
What is an over-the-counter topical cream for herpes that blocks viral entry if used within 12hours of
onset? - Ans:✔✔-Docosanol
What is a topical gel applied to HPV warts? - Ans:✔✔-podofilox
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