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BARRY BMS BIOCHEMISTRY I Q&A 2024

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BARRY BMS BIOCHEMISTRY I Q&A 2024

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  • October 24, 2024
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BARRY BMS BIOCHEMISTRY I
Zwitterionic Ion - Answers-form of aa. that exists in physiological pH 7.3-7.4

True or False. The R Group is attached to the alpha carbon in an amino acid. -
Answers-True.

True or False.20 core amino acids are chiral compounds with the exception of glycine -
Answers-True

If an amino acid has a high Ka, what does that mean in regards to protonation? -
Answers-The more likely the functional group is to be ionized a physiological pH as a
proton is donated

True or False. If an amino acid has a high Ka and a low pka, that means it is a weak
acid - Answers-False. It is a strong acid.

True or False. There is variable flexibility within the peptide bond - Answers-False.
There's flexibility on either side of the peptide bond

Peptide bonds
a) rigid covalent bonds
b) stable
c)ionized a physiological pH
d) all of the above
e) a & b - Answers-Answer: e

Amino Acids are said to be positioned in the _________ position.
a) steric
b) cis
c) trans
d) none of the above - Answers-c

The primary structure...
a) alpha amino end and carboxylate end relate to arrangement of DNA molecule
b) largely determined by sequence of DNA Bases
c) determines the functional 3-D shape of a protein
d) all of the above - Answers-d) all of the above

What causes the activation of proinsulin? - Answers-Releasing of the C peptide due to
proteolytic cleavage between residues 30-31 and 65-66

What causes HbS?? - Answers-A single amino acid substitution in the B chain. Valine
and Glutamate are switched.

What type of bond stabilizes Secondary Protein Structure? - Answers-Hydrogen Bonds

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