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CIC: Practice Exam 1 Questions and Answers (Latest update 2025)
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CIC: Practice Exam 1 Questions and Answers (Latest update 2025)
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CIC: Practice Exam 1 Questions andAnswers (Latest update 2025)
1. The bacterium most likely to be transmitted from mother
to infant during labor and cause neonatal sepsis is:
a. Escherichia coli
b. Staphylococcus aureus
c. Group B Streptococcus
d. Group A Streptococcus - Correct Answer ✅Group B
Streptococcus
Rationale: In Group B Streptococcus (GBS) neonatal
infections, heavy maternal colonization is associated with an
increased risk for preterm labor, which in turn is a significant
risk factor for neonatal infection. Intrauterine
infection of the fetus therefore likely occurs via ascending
spread of GBS from the vagina of a pregnant,
asymptomatically colonized woman and subsequent rupture
of membranes before 37 weeks' gestation.
Reference: APIC Text, 4th edition, Chapter 94 - Streptococci
,CIC: Practice Exam 1 Questions and
Answers (Latest update 2025)
2. Which of the following is an example of the criterion of
"Strength of the Association" from Hill's criteria for causation?
a. In a study of the association between antibiotic exposure
and development of C. difficile infection, the odds ratio was
2:3
b. In a study of the association between antibiotic exposure
and development of C. difficile infection, the authors'
conclusions are consistent with those of three other studies
c. In a study of the association between antibiotic exposure
and development of C. difficile infection, antibiotic therapy
began an average of 3 weeks before C. difficile infection
developed
d. In a study of the association between antibiotic exposure
and development of C. difficile infection, prolonged antibiotic
therapy was a greater risk factor for C. difficile infection than
short-term antibiotic therapy - Correct Answer ✅In a study
of the association between antibiotic exposure and
development of C. difficile infection, the odds ratio was 2:3
Rationale: Causal associations exist when evidence indicates
that one factor is clearly shown to increase the probability of
,CIC: Practice Exam 1 Questions and
Answers (Latest update 2025)
the occurrence of a disease. In a causal relationship, the
reduction or diminution of a factor decreases the frequency of
the disease being studied.
The criteria currently used for causality were developed by
Austin Bradford Hill and are known as Hill's criteria. These
criteria use modern epidemiological methods to determine
whether a factor is causal for a given disease. Strength of
association is the first criterion: The incidence of disease
should be higher in those who are exposed to the factor
under consideration than in those who are not exposed; that
is, the stronger the association between an exposure and a
disease, the more likely the exposure is to be causal.
The odds ratio is a statistical measure that gives us an
indication of how strongly the risk factor is associated with
the disease outcome.
Reference: APIC Text, 4th edition, Chapter 10
, CIC: Practice Exam 1 Questions and
Answers (Latest update 2025)
3. Which of the following rules should be followed when
collecting a stool sample for C. difficile testing?
1) Stool sample should be freshly passed within 1-2 hours
2) 10-20rnL. of formed stool should be collected
3) Stool should be passed into a clean, dry container
4) Specimens should be obtained before antimicrobial agents
have been administered
a. 1,2
b. 2,3
c. 1,3
d. 1,4 - Correct Answer ✅1, 3
1) Stool sample should be freshly passed within 1-2 hours
3) Stool should be passed into a clean, dry container
Rationale: The accuracy of all tests depends on proper
specimen handling and transport. The following rules should
be followed when collecting samples for C. difficile testing:
• Stool samples should be freshly passed within 1-2 hours
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