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BMSC 207 Cell membranes Latest Questions & Answers Verified 100% Correct

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  • BMSC 207 Cell Membranes

Adipose tissue vs skeletal muscle - ️️Adipose: - ~ 90% lipids, small fraction of water Skeletal: - ~75% water ~18% protein Cell membrane (plasma membrane) - ️️- double layer (lipid bilayer) with phospholipids and protein molecules inserted in them - Carbohydrates are attached to extr...

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  • October 25, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • BMSC 207 Cell membranes
  • BMSC 207 Cell membranes
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PatrickKaylian
BMSC 207 Cell membranes
Adipose tissue vs skeletal muscle - ✔️✔️Adipose:
- ~ 90% lipids, small fraction of water
Skeletal:
- ~75% water
~18% protein

Cell membrane (plasma membrane) - ✔️✔️- double layer (lipid bilayer) with
phospholipids and protein molecules inserted in them
- Carbohydrates are attached to extracellular side

Sphingolipid chemical composition and function - ✔️✔️- sphingosine backbone with
fatty acid tail, as well as possible cholines, sugars, attached.
-Longer than phospholipids
- act as Lipid rafts of the cell membrane

Body cavities - ✔️✔️Cranial, thoracic, pelvic

Functional body compartments - ✔️✔️ECF, ICF, cells

Functions of a cell membrane - ✔️✔️- physical isolation separating ICF and ECF as
well as the cell from its environment
- Regulation of exchange with the environment; selectively permeable
- Communication between the cell and its environment ; proteins allow for responding
and interacting
- Structural support; proteins in the membrane make cell-to-cell connections (tissue)
and anchor the cytoskeleton

Cell membrane composition (% of each) - ✔️✔️- 55% proteins
- 45% lipids
- small amount of carbohydrates

- note not all membranes are the same

what determines the amount of protein a cell membrane contains? - ✔️✔️- The more
metabolically active the membrane is the more protein it contains
- how much energy it needs to produce

The 3 lipid types in the cell membrane and its % composition - ✔️✔️- Phospholipid;
approx 50%
- Sphingolipids; approx 30%
- Cholesterol; approx 20%

, Amphipathic - ✔️✔️has both a hydrophilic and hydrophobic side

Phospholipid bilayer - ✔️✔️flat, sheet layer, forms when environment is purely liquid
and no air

Micelles - ✔️✔️Spherical droplets of phospholipids; important in lipid digestion

Liposomes - ✔️✔️Spherical bilayers produced in a lab to get certain substances (ie
drugs) across a cell membrane. Has an aqueous center where the certain substance is
located

Phospholipid chemical composition and function - ✔️✔️- glycerol backbone with fatty
acid tail
- major lipid that makes up most of the cell membrane


Cholesterol Function - ✔️✔️-Increases viscosity, decreases permeability
- shimmies in between phospholipids ; extra security guard for the membrane
- makes membrane less delicate

Current cell membrane model is called - ✔️✔️fluid mosaic model

What does the extracellular surface of the cell membrane contain? - ✔️✔️-
glycoproteins and glycolipids;
- carbohydrates are attached either to proteins or lipids

How many different types of proteins does each cell have in its membrane? - ✔️✔️10-
50 different types

Integral proteins - ✔️✔️- tightly bound to the membrane, bound to fatty acid or external
GPI anchor
- you need to disrupt/damage the cell membrane to remove/isolate it


Integral protein roles - ✔️✔️- membrane receptors
- cell adhesion molecules
- transmembrane movement
- enzymes
- mediators of intracellular signalling

Peripheral protein roles - ✔️✔️- participate in intracellular signalling
- form submembraneous cytoskeleton

Lipid anchored proteins - ✔️✔️- commonly associated with sphingolipids

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