Signs and symptoms of anxiety and depression can heighten pain ________.
awareness
What are pain sensitive structures within the cranium?
venous sinuses, dura, arteries of the dura
Tension type and migraine HAs are ________ HAs.
primary
TMJD is a ________ HA.
secondary
What HA?
-bilateral
-pressing or tightening quality without pulsation
-mild to moderate intensity
-not exacerbated by routine physical activity
tension
Increased _________ muscle tenderness is the most common abnormal finding on exam
in pt's with tension HA.
pericranial
What HA?
,-pulsatile quality of HA
-4-72 hours in duration
-unilateral location
-nausea or vomiting
-disabling intensity
migraine
Triptans, dihydroergotamine, ergotamine, CGRP antagonists are all ________
medications for severe migraines.
abortive
If a pt requires acute tx of migraine more than 2 times per week, they should be on
_______ tx.
prophylactic
A self-propagating wave of neuronal and glial depolarization that spreads across the
cerebral cortex that can cause the aura of migraine, activate the trigeminal nerve
afferents, or later the blood-brain barrier permeability.
cortical spreading depression
Pathophysiology of migraine involves activation of the _________ system.
trigeminovascular
What spinal nerves come together in the trigeminal nucleus caudalis in the brainstem?
C1-C3
Signal goes from the trigeminal nucleus ________ in the brain stem to the trigeminal
nerve which feeds the sensation of the face.
caudalis
, The sensory neurons of the trigeminal nerve innervate large cerebral vessels, pial
vessels, dura mater, and large _______ ______.
venous sinuses
From the trigeminal nucleus caudalis, fibers that are involvd in the localization of
________ ascend to the thalamus and to the sensory cortex.
pain
Stimulation of the trigeminal ganglion results int he release of what vasoactive peptides
that are associated with the process of neurogenic inflammation?
substance P, CGRP, neurokinin A
What vasoactive peptide is a potent vasodilator of cerebral and dural vessels and can
trigger migraine attacks?
CGRP
Migraines beget migraines because of _________.
sensitization
The process in which neurons become increasingly responsive to nociceptive and
non-nociceptive stimulation, resulting in the pain threshold int he CNS being lowered.
sensitization
Where does CN V3 and the middle meningeal artery exit the cranium?
foramen ovale
What somatic dysfunctions can affect CN V?
temporal, sphenoid
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