Regis NU641 Adv Clinical Pharmacology
Midterm Exam with correct answers
Patients that are at highest risk for abruptly stopping a beta blocker are those with -
correct answer -Angina, Coronary Artery Disease, & Migraines
The medication that helps the imbalance between myocardial oxygen supply and
myocardial oxygen demand in the myocardium by increasing the myocardial
oxygen supply - correct answer -Angiotensin-converting enzyme (ACE) inhibitors
Roles of Angiotensin-converting enzyme (ACE) inhibitors in DM patients - correct
answer -improves insulin sensitivity
improves renal hemodynamics
reduce production of angiotensin II
The pathological change that takes place in HF that is not addressed by ACE
inhibitors - correct answer -Activation of the sympathetic nervous system that
increases heart rate and preload
Reason why nitro glycerin tablets "do not work well" in patient with hyperlipidemia
and angina age - correct answer -blunted coronary artery dilation due to calcified
plaque
Clinical judgement in prescribing includes - correct answer -factoring in the cost to
the patient of the medication prescribed
Prior to prescribing an ACE inhibitor the NP should access for - correct answer -
decreased renal function
First-line pharmacologic therapy for hyperlipidemia - correct answer -statins
When is consultation with or referral to a cardiologist appropriate? - correct answer -
Any end-organ damage, direct effects on lifestyle, or inability to perform the tasks
of daily living
, If not chosen as the first drug in hypertension treatment, which drug class should be
added as a second step because it will enhance the effects of most other agents? -
correct answer -Diuretics
A 65-year-old patient who has been on a lipid-lowering diet and is using plant sterol
margarine daily for the past three months. Her LDL is 135mg/dL. What would an
appropriate treatment for them be? - correct answer -Determine their other risk
factors
Calcium Channel Blocker's helps control blood pressure because it - correct answer -
promote smooth muscle dilation by stopping intracellular entry of calcium into the
cell, which increases contractility, which increase the activity of the NA+/K+/ATPase
pump indirectly
Patient education regarding prescribed medications includes - correct answer -
discussion of expected adverse drug reactions
Patient education when prescribing clopidogrel includes which of the following
statements? - correct answer -Do not take any herbal products without first
discussing this with the provider
When starting a patient on a statin, what would education include? - correct answer
-If they stop the medication, their lipid levels will return to pretreatment levels;
medication is a supplement to diet therapy and exercise; and if they have muscle
aches or pain, they should contract their provider
When treating a patient for hypertension with a non-selective beta blocker, what
other organ may be unintentionally affected? - correct answer -Lung
When writing a prescription for warfarin it is common to write this on the
prescription - correct answer -The brand name of warfarin and "do not substitute"
Which formulation of nitrate may be most cost effective for the patient who rarely
has the need for dosing? - correct answer -Sublingual tablets
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