Pharm II - Final Exam
Right - ANS Which side of the heart affected by infective endocarditis rarely requires surgery for
treatment?
Bactericidal - ANS What type ABX are required to treat infective endocarditis?
Staph, Strep, Enterococci - ANS What are the most common bacterial causes of infective endocarditis?
Candida and Aspergillus - ANS What fungal species are common causes of infective endocarditis?
Modified Duke - ANS What is the governing criteria for diagnosing infective endocarditis?
Vancomycin - ANS Best empiric ABX for Gram (+) coverage in infective endocarditis
Daptomycin - ANS Best empiric ABX for infective endocarditis if Pt has vancomycin allergy
Ceftriaxone (Rocephin) or cefazolin (Ancef) - ANS What are the best empiric ABX for Gram (-) coverage
in infective endocarditis if Pt has a native valve?
Vancomycin + Ceftriaxone - ANS What is the most common empiric ABX combo for infective
endocarditis?
Histamine Release Syndrome - ANS What will happen is vancomycin is pushed to quickly?
Gentamicin - ANS What ABX do you add if Strep endocarditis is PCN resistant?
, Pen G, Ampicillin, Amoxicillin, Ceftriaxone, Vancomycin - ANS What are the main options for Strep
endocarditis?
Cefazolin, Oxacillin, Nafcillin - ANS What are the main options for MSSA endocarditis?
Vancomycin, Daptomycin +/- ceftaroline, Linezolid - ANS What are the main options for MSSA
endocarditis? (MRSA Meds)
Rifampin - ANS If Pt has prosthetic valve, what should be added to treat Staph (MSSA/MRSA)
endocarditis?
Pen G, Ampicillin, Amoxicillin, Vancomycin - ANS What are the main options for Enterococci
endocarditis?
Ceftriaxone - ANS What are the main options for HACEK endocarditis?
Vancomycin + Cefepime - ANS What is the treatment for acute (days) blood culture-negative
endocarditis in a Pt with a native valve?
Vancomycin + Rifampin + Gentamicin + Cefepime - ANS Pt has had prosthetic valve for < 1 yr. What is
the treatment for blood culture-negative endocarditis?
Vancomycin + Amp/Sulbactam - ANS What is the treatment for subacute (weeks) blood culture-negative
endocarditis in a Pt with a native valve?
Vancomycin + Ceftriaxone - ANS Pt has had prosthetic valve for > 1 yr. What is the treatment for blood
culture-negative endocarditis?
Amphotericin B - ANS What is the treatment for fungal endocarditis?
Right - ANS Which side of the heart affected by infective endocarditis rarely requires surgery for
treatment?
Bactericidal - ANS What type ABX are required to treat infective endocarditis?
Staph, Strep, Enterococci - ANS What are the most common bacterial causes of infective endocarditis?
Candida and Aspergillus - ANS What fungal species are common causes of infective endocarditis?
Modified Duke - ANS What is the governing criteria for diagnosing infective endocarditis?
Vancomycin - ANS Best empiric ABX for Gram (+) coverage in infective endocarditis
Daptomycin - ANS Best empiric ABX for infective endocarditis if Pt has vancomycin allergy
Ceftriaxone (Rocephin) or cefazolin (Ancef) - ANS What are the best empiric ABX for Gram (-) coverage
in infective endocarditis if Pt has a native valve?
Vancomycin + Ceftriaxone - ANS What is the most common empiric ABX combo for infective
endocarditis?
Histamine Release Syndrome - ANS What will happen is vancomycin is pushed to quickly?
Gentamicin - ANS What ABX do you add if Strep endocarditis is PCN resistant?
, Pen G, Ampicillin, Amoxicillin, Ceftriaxone, Vancomycin - ANS What are the main options for Strep
endocarditis?
Cefazolin, Oxacillin, Nafcillin - ANS What are the main options for MSSA endocarditis?
Vancomycin, Daptomycin +/- ceftaroline, Linezolid - ANS What are the main options for MSSA
endocarditis? (MRSA Meds)
Rifampin - ANS If Pt has prosthetic valve, what should be added to treat Staph (MSSA/MRSA)
endocarditis?
Pen G, Ampicillin, Amoxicillin, Vancomycin - ANS What are the main options for Enterococci
endocarditis?
Ceftriaxone - ANS What are the main options for HACEK endocarditis?
Vancomycin + Cefepime - ANS What is the treatment for acute (days) blood culture-negative
endocarditis in a Pt with a native valve?
Vancomycin + Rifampin + Gentamicin + Cefepime - ANS Pt has had prosthetic valve for < 1 yr. What is
the treatment for blood culture-negative endocarditis?
Vancomycin + Amp/Sulbactam - ANS What is the treatment for subacute (weeks) blood culture-negative
endocarditis in a Pt with a native valve?
Vancomycin + Ceftriaxone - ANS Pt has had prosthetic valve for > 1 yr. What is the treatment for blood
culture-negative endocarditis?
Amphotericin B - ANS What is the treatment for fungal endocarditis?
