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NRSG 3100 Unit 4 Question and answers 100% correct $13.49   Add to cart
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NRSG 3100 Unit 4 Question and answers 100% correct

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NRSG 3100 Unit 4 Question and answers 100% correct NRSG 3100 Unit 4 Piperacillin and tazobactam (Zosyn) - correct answer Indication: skin, blood, sinus, CNS, respiratory infections MOA: inhibit bacterial wall synthesis, greater penetration through outer membrane of gram negative bacteri...

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  • October 26, 2024
  • 10
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • NSG 3100
  • NSG 3100

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NRSG 3100 Unit 4
Piperacillin and tazobactam (Zosyn) - correct answer ✔Indication: skin,
blood, sinus, CNS, respiratory infections


MOA:
inhibit bacterial wall synthesis, greater penetration through outer membrane of
gram negative bacteria. Tazobactam added to help avoid inactivation by
certain bacteria.


Contraindications/precautions:
-Caution with initial doses, can cause anaphylaxis
-When taken with coagulation modifiers, **can increase bleeding time
-HF patients can have sodium overload-Safe in pregnancy (category B)


Adverse Effects:
-Rash, diarrhea
-Causes platelet aggregation --> prolongs bleeding time
- Pseudomembranous colitis, confusion, seizures are rare


cefazolin (Kefzol, Ancef) - correct answer ✔MOA:
-Inhibits bacterial wall synthesis
-Bacteriocidal-Broad spectrum
- Penetrates bones really well


Contraindications/Precautions:
-Allergic to any drug in the cephalosporin class

, -Monitor patients with renal impairment
- excreted unchanged by kidneys


Drug Interactions:
-Nephrotoxicity with concurrent use of nephrotoxic drugs (aminoglycosides,
vancomycin)
-Synergistic antimicrobial action with other antibiotics (carbapenems,
penicillins)
-Increased anticoagulant effect of warfarin


ceftriaxone (Rocephin) - correct answer ✔Crosses BBB


Longer durations that allow for once-daily dosing


•Sometimes a preferred drug for use during pregnancy


•High incidence of pseudomembranous colitis


•IM administration (large muscle, may use lidocaine)


imipenem-cilastin (Primaxin) - correct answer ✔MOA:
-Inhibits bacterial wall synthesis
-Bacteriocidal
-Broad spectrum
-effective against most gram-positive and gram-negative microbes, including
anaerobic bacteria

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