1. Cancer is associated with?
Answer
Altered expression of cellular genes that are re- sponsible for proliferation and differentiation
2. What characteristics of benign tumors can make them potentially lethal?
Answer
1. Proximity to critical structures (obstructing airway, growth in brain creating increased
intracranial pressure)
2. Some benign cells have shown potential to become malignant
3. Describe the common characteristics of benign tumors
Answer
1. Do not invade adjacent tissue
2. typically encapsulated
3. Resemble their tissue of origin (liver, skin)
4. is a lack of differentiated features in malignant cells.
What is this correlated with?
Answer
Anaplasia More aggressive tumors
5. What characteristic determines the diagnosis of malignancy?
Answer
Invasion of local tissue or metastasis to distant sites
6. The growth rate of tumors is typically slow whereas the growth rate of
tumors is rapid
Answer
Benign
Malignant
, 7. tumors rarely have areas of necrosis and tend to maintain structure similar to their
cells of origin.
tumors often have areas of necrosis and have abnormal shape and size
Answer
Benign
Malignant
8. The great majority of human cancers (90%) are carcinomas from malignant transformation
of?
Answer
Epithelial cells
9. List some abnormal behaviors of cancer cells that allow them to prolifer- ate?
Answer
1. Cancer cells proliferate despite lack of growth-initiating signals from the environment
2. Cancer cells escape apoptotic signals
3. Cancer cells are genetically unstable and evolve by accumulating new mutations at a much
faster rate than normal cells
4. Cancer cells develop proangiogenic signaling abilities allowing them to create their own
vascular supply
5. Cancer cells develop the ability to evade immune surveillance and destruction
10. Americans have an almost lifetime risk of developing cancer
Answer
One in Three
11. What are some modifiable risk factors that can influence cancer risk?
Answer
To- bacco and Alcohol use, obesity, Nutrition, Sun exposure
12. What exposure increases the risk of cancers in the anogenital, head and neck, and liver?
Certain viruses increase the risk of cancer in these areas
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller gradexam. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $16.99. You're not tied to anything after your purchase.