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Lecture notes of 7 pages for the course Bio 160 at Mesa Community College (Notes)

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  • October 26, 2024
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[LECTURE STUDY GUIDE] Unit 2


Unit Objectives:
 Describe the structure and function of the skeletal system and joints
 Describe the structure and function of the muscular system
 Describe the structure and function of the nervous system

Relevant Topics in Textbook:
Chapter 7 Skeletal System
Chapter 8 Muscular System
Chapter 9 Nervous System
Chapter 10 The Senses

Lecture Exam Review Questions: Lectures 8 and 9

Bone (our skeleton is living tissue)

1. List the functions of bone:

 Support, protection, body levers, new blood cell formation, and calcium homeostasis



2. Know the cells, matrix and organization of bone and associated tissues. Define the following terms:

a) Periosteum and Endosteum
 Periosteum – connective tissue on outer layer of bones
 Endosteum – Lines inner layer of bone
b) Compact vs Trabecular bone
 Compact bone – very dense bone
 Trabecular bone (spongy bone) – less dense bone with pockets or holes

c) Osteogenic stem cells, Osteoblasts, Osteocytes, Osteoclasts
 Osteogenic stem cells – stem cells divide and produce new stem cells and differientate
into new osteoblasts and chondroblasts
 Osteoblasts – synthesize new bone matrix
 Osteocytes – mature osteoblasts that become surrounded with bone matrix
 Osteoclasts – derived from blood precursor cells, very large and multinucleated, reabsorb
bone and remove matrix degrading collegan and releasing calcium

d) Chondroblasts and Chondrocytes
 Chondroblasts – produce cartilage
 Chondrocytes – produce cartilage matrix
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, [LECTURE STUDY GUIDE] Unit 2

e) Collagen and Hydroxyapatite (bone matrix)
 Collagen – provides flexibility within bones
 Hydroxyapatite – provides strength and bone regeneration


3. Briefly describe the 2 types of bone formation (intramembranous and endochondral ossification).
You do not need to memorize the actual steps to either form of ossification, but you should know:

a) What is the starting template for each type?

 Endochondral – hyaline cartilage is made by chondroblasts then ossification if the
cartilage is done by osteoblasts
 Intramembranous – embryonic stem cells or mesenchymal stem cells create sheets of
collagen connective tissue then osteoblasts ossify into new bone


b) What types of bones are formed using these 2 types of bone formation?

 Intramembranous – flat bones
 Endochondral – long bones


4. What is achondroplasia?

a) What bones are affected?
Long bones

b) What type of ossification is not occurring properly and why?

Endochondral because the defect is a failure to elongate growth plates which is a cartilage formation problem


5. Bones cannot get longer after the growth plates close, but they do change…this is called
remodeling.

a) Describe how bones can change in the adult skeleton:
Bones can regenerate new bone cells or break down bone cells we don’t use



b) How does bone density change as we age?
Lose density with age


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