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Pharmacology chapter 17 (Final Exam) Questions And Answers 100% Pass.

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  • Pharmacology
  • Institution
  • Pharmacology

ct process - answerwhat are the 4 mechanisms of adrenergic receptor activation? sympathetic nerve terminals - answerNorepinephrine is released when drug acts on ____ amphetamines - answerwhat drugs are an example of promotion of NE release? TSAs - answerwhat drugs are an example of blockade of ...

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  • October 29, 2024
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  • Exam (elaborations)
  • Questions & answers
  • Pharmacology
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©BRIGHTSTARS EXAM SOLUTIONS
10/22/2024 12:14 PM


Pharmacology chapter 17 (Final Exam)
Questions And Answers 100% Pass.



Antagonists - answer✔what type of drugs only have affinity and lack intrinsic activity?

agonist - answer✔what type of drugs have both affinity and intrinsic activity

adrenergic receptors - answer✔activation of what receptors causes responses That are Identical
to When the SNS is Stimulated with Endogenous Molecules?
-receptor binding (direct process)
-promotion of NE release (indirect process)
-blockade of NE reuptake (indirect process)

-inhibition of NE inactivation (indirect process - answer✔what are the 4 mechanisms of
adrenergic receptor activation?

sympathetic nerve terminals - answer✔Norepinephrine is released when drug acts on ____

amphetamines - answer✔what drugs are an example of promotion of NE release?

TSAs - answer✔what drugs are an example of blockade of NE reuptake?

MAO inhibitors and COMT inhibitors - answer✔what drugs are an example of inhibition of NE
inactivation?

MAO and COMT - answer✔what two enzymes are found in the liver and intestine and inactivate
norepinephrine?

catecholamines and noncatecholamines - answer✔what are the two chemical classes of
adrenergic agonists?

catecholamines - answer✔which adrenergic agonist class cannot be used orally (because they
will become inactivated prior to reaching the CNS d/t MAO and COMT), have a brief duration

, ©BRIGHTSTARS EXAM SOLUTIONS
10/22/2024 12:14 PM

of action (Need to be given frequently or via continuous infusion because of rapid inactivation),
and cannot cross the BBB (because they are water soluble)?

Nonchatecholamines - answer✔which adrenergic agonist class can be administered orally
(because they are very slowly metabolized by MAO, and COMT doesn't effect them), have a
much longer half life, and more able to cross the BBB (because they are lipid soluble)?

receptor selectivity - answer✔•These Medications Differ Widely With Respect to the Receptors
They Can Activate
•High Variability Exists in Receptor Selectivity Among the Adrenergic Agonists
•Note: Ability of a Drug to Selectively Activate Certain Receptors and Not Others is Dependent
on Dosage:
-Low Dose = Maximal Selectivity
-High Dose = Decline in Selectivity

alpha 1 - answer✔which receptor site, when stimulated causes mydriasis and vasoconstriction
(which causes increased BP)?

Alpha 2 - answer✔which receptor site, when activated, works in the CNS to reduce
norepinephrine outflow to the heart and blood vessels and relieves severe pain?

relaxation - answer✔at GI smooth muscle, Alpha 1 receptors cause ____ of muscle

blood vessels, eye, bladder, prostate, and uterus - answer✔alpha 1 receptors produce contraction
of smooth muscle in which five areas?

glycogenolysis - answer✔what occurs in the liver when alpha 1 receptors are stimulated?

increased secretions - answer✔what occurs at the salivary glands when alpha 1 receptors are
stimulated?
-Hemostasis- d/t vasoconstriction
-Nasal Decongestion- d/t alpha 1 vasoconstriction
-Adjunct to Local Anesthesia- delays systemic absorption and reduced blood flow to site
-Elevation of Blood Pressure

-Mydriasis (only use not based on vasoconstriction)- helps with eye exams - answer✔what are
the five therapeutic applications of alpha 1 activation?
-Hypertensive

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