MCN 568 ADVANCED PHARMACOLOGY FINAL EXAM
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Pulmonary venous return enters the left atrium through a right to left shunt
across the foramen oval or ASD in this CHD
Correct Answer -TAPVR
In this type of TAPVR, the pulmonary veins drain to a confluence, which
drains a left vertical vein, to the inominate vein, to the right atrium. Affected
infants present with mild to moderate cyanosis. 50 % incidence of TAPVR
Correct Answer -supracardiac
In this type of TAPVR, the pulmonary venous confluence drains to the right
atrium via the coronary sinus. Affected infants will present with mild to
moderate cyanosis. 20% incidence of TAPVR
Correct Answer -cardiac
In this type of TAPVR, it is characterized by obstructed pulmonary enous
return below the diaphram. Most serious form
Correct Answer -Infracardiac
In this CHD, males are affected four times more often than females
Correct Answer -TAPRV
In this CHD, infant is profoundly ill and presentation mimics severe lung
disease and PPHN.
Correct Answer -TAPVR
,A distinguishing finding of this CHD on CXR that differentiates it from RDS is
that air bronchograms are not seen
Correct Answer -TAPVR
This CHD is often times confused with RDS due to the cxr findings and
clinical presentation
Correct Answer -TAPVR
Obstruction to pulmonary venous return causes severe pulmonary venous
hypertension, pulmonary edema, reflex pulmonary venous constriction and
subsequently pulmonary artery hypertension are present in this CHD
Correct Answer -TAPVR
Lithium taken early in pregnancy results in this cardiac anomaly
Correct Answer -Epsteins anomaly
VSD, and pulmonary stenosis or atresia are associated lesions of this
cardiac anomaly
Correct Answer -Epstein's anomaly
In the most severe cases of this anomaly, it is ductal dependent and infant
presents with severe cyanosis and O2 saturation is less than 75%. What
medication is required?
Correct Answer -Epstein's anomaly and PGE
,In severe cases, CHF and hepatomegaly are present
Correct Answer -Epstein's anomaly
A gallop is commonly heard with?
Correct Answer -Epstein's anomaly
A systolic murmur can vary from soft to loud depending on the degree of
tricuspid regurgitation and pulmonary artery pressure in?
Correct Answer -Epstein's anomaly
In very severe cases, in utero cardiac enlargement leads to lung hypoplasia
Correct Answer -Epstein's anomaly
Heart appears " balloon-shaped" on CXR
Correct Answer -Epsteins anomaly
Cyanotic Ductal Dependent CHD's
Correct Answer -Transposition of the great arteries
Tricuspid atresia
, Pulmonary atresia
Tetralogy with severe PS or atresia
Severe Epstein's
Dosing of PGE
Correct Answer -0.05-1 mcg/kg/min
may increase to 0.2-0.4 mcg/kg/minute if there is no response
True or False? PGE may be infused in IV site with maitenance fluids
Correct Answer -False
True or False? PGE is compatible with D5W, D10W or NS but not with other
medications
Correct Answer -True
In order for oxygenated blood to reach the systemic circulation in this CHD,
mixing of the pulmonary and systemic venous return must occur at one or
more of the 3 locations: PFO, ASD, VSD, PDA
Correct Answer -TGA
A VSD is present in 40-50% of these patients
Correct Answer -TGA
In this CHD, if the VSD is sizable, mild cyanosis with crying may be present.
CHF ( seen as tachypnea, tachycardia, hepatomegaly and a loud murmur are
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