EDAPT- pharmokinetics Exam Practice Questions and Answers
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Course
2024/2025
Institution
2024/2025
EDAPT- pharmokinetics Exam Practice
Questions and Answers
Which step describes the biochemical alteration of a drug into an active or inactive metabolite? -
ANSWER-metabolism
What is pharmacokinetics? - ANSWER-What happens to the drug from the time is enters the body
until it leaves
Steps in ...
Distribution is the transport of a drug through the bloodstream to its site of action--Distribution
Biochemical alteration of a drug into an active or inactive metabolite--Metabolism
Using the drop-down menus, select the words that complete the sentences accurately. - ANSWER✔✔-A
drug entering the body through the oral route is first ABSORBED in the INTESTINE and goes through the
liver in something called FIRST PASS metabolism. It then goes through DISTRIBUTION by binding to
plasma PROTEINS for transport throughout the body. Unbound drug is considered a(n) FREE drug, and is
active in the blood.
If two drugs both go through the cytochrome p450 3A4 enzyme system in the liver, which statement
accurately describes what occurs? - ANSWER✔✔-One drug blocks the other one, thereby increasing the
amount of the second drug.
Which factor affects absorption in an elderly patient? - ANSWER✔✔-Decreased gastric pH
The half-life of morphine is 2 hours. How long would it take for morphine sulfate to get to steady state in
someone provided the maintain the same strength and dose? - ANSWER✔✔-10 hours
How are most medications transported through the body? - ANSWER✔✔-bound to proteins
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