NUR 641E Final Exam Questions And Answers Verified 100% Correct
2 views 0 purchase
Course
NUR 641E
Institution
NUR 641E
NUR 641E Final Exam Questions And
Answers Verified 100% Correct
Half-life - answer --how long it takes for drug to be excreted from the body
-determines frequency of administration
-predicts how long toxic effects can last
first-order (linear) pharmacokinetics - answer -metabolism is direct...
NUR 641E Final Exam Questions And
Answers Verified 100% Correct
Half-life - answer --how long it takes for drug to be excreted from the body
-determines frequency of administration
-predicts how long toxic effects can last
first-order (linear) pharmacokinetics - answer -metabolism is directly proportional
to the free concentration of the drug
zero-order (nonlinear) pharmacokinetics - answer -drug is metabolized at a
constant rate per unit of time
CYP3A4 substrates - answer -may have decreased activity if any CYP3A4 inducer
drugs are used along with it
Discovery - answer -laboratory research to develop the new drug
Preclinical research - answer -animal testing for safety
Phase I - answer -clinical research on healthy human subjects to assess medication
PK
Phase II - answer -clinical research in humans primarily for medication safety
usually in a population for which the treatment is intended
Phase III - answer -clinical research in humans comparing the new drug to
accepted medications or placebo for efficacy and safety
Phase IV - answer -post marketing surveillance. Reporting of adverse effects not
identified in earlier clinical studies
medication safety organizations - answer --ISMP
,-IOM
-Joint Commission
-NCC MERP
-FDA Safe Use Initiative
pharmacological ADR - answer --80-90% of ADRs
-an extension of the pharmacological affect of the drug
-ex. overdose
idiosyncratic ADR - answer --separate from the pharmacological affect of the drug
-commonly immune mediated response
does not - answer -the FDA does/does not mandate that ADRs be reported
Polypharmacy - answer -involves using multiple health care providers for care,
using multiple medications, and using several pharmacies for prescription filling
ACEI - answer --Lisinopril, captopril, enalopil, ramipril, benazepril, fosinopril
-suppress the release of ACE
ACEI (side effects) - answer --cough
-angioedema
-discontinue the ACEI if angioedema occurs
ARBs - answer --block angiotensin II receptors
primary hypertension - answer --denotes high blood pressure from an unidentified
cause; also called essential hypertension
-90% of cases
secondary hypertension - answer --high blood pressure caused by the effects of
another disease
-example: chronic renal failure
beta-1 stimulation - answer --increased HR
-increased BP
-increased CO
beta-1 blockade - answer --reduced heart rate
-reduced BP
-reduced CO
beta agonists - answer --isoproternol
LHF - answer --decreased delivery of O2 to body tissues
Absorption - answer -from the administration site either directly or indirectly into
the blood/plasma
Distribution - answer -Reversibly or irreversibly move from bloodstream into the
interstitial and intracellular fluid
Metabolism - answer -Biotransformed via hepatic metabolism or by other tissues
Elimination - answer -Lastly, the drug and its metabolites are eliminated from the
body
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller TheExamMaestro. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $11.99. You're not tied to anything after your purchase.
