Red Blood Cells and Erythropoiesis Exam Study Guide Questions and Answers
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Course
Red Blood Cells
Institution
Red Blood Cells
Red Blood Cells and Erythropoiesis Exam
Study Guide Questions and Answers
Where does RBC production occur? - ANSWER-bone marrows of sternum, ribs, and pelvis
What is the pathway of RBC production? - ANSWER-EPO (made in kidney)-->EPOr (on RBC
progenitors)-->JAK2 pathway-->RBC production...
What are reticulocytes? - ANSWER✔✔-young blood cells with some ribosomal RNA remaining that gives
the cell a blue hue
circulate for 1-2 days
What is the life span of a mature RBC? - ANSWER✔✔-120 days
What vitamins/minerals do you need for DNA synthesis? - ANSWER✔✔-B12 and folate
What vitamins/minerals do you need for hemoglobin synthesis? - ANSWER✔✔-Iron, Globin, Heme, and
Amino Acids
What is the Pentose Phosphogluconate Pathway? - ANSWER✔✔-G6PD maintains NADPH levels, which
maintains reduced glutathione to rid the cell of free radicals
This prevents oxidative damage to the global chains and subsequent denaturation
What does pyruvate kinase do? - ANSWER✔✔-ensures adequate ATP production by the RBC
What is the structure of RBCs? - ANSWER✔✔-anucelate in the peripheral blood
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