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Biology Ch 15 Fifth Edition Brooker BRCC 1033 Exam Practice Questions and Answers $12.49   Add to cart

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Biology Ch 15 Fifth Edition Brooker BRCC 1033 Exam Practice Questions and Answers

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Biology Ch 15 Fifth Edition Brooker BRCC 1033 Exam Practice Questions and Answers Figure 15.1 A missense mutation that causes red blood cells to sickle in sickle cell disease. Scanning electron micrographs of (a) a normal red blood cell and (b) a sickled red blood cell. As shown above the micr...

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  • October 31, 2024
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Biology Ch 15 Fifth Edition Brooker BRCC

1033 Exam Practice Questions and

Answers


Figure 15.1 A missense mutation that causes red blood cells to sickle in sickle cell disease. Scanning

electron micrographs of (a) a normal red blood cell and (b) a sickled red blood cell. As shown above the

micrographs, a missense mutation in the β-globin gene (which codes for a subunit of hemoglobin)

changes the sixth amino acid in the β-globin polypeptide from glutamic acid (Glu) to valine (Val). (c) This

micrograph shows how this alteration to the structure of β-globin causes the formation of abnormal

fiber-like structures. In normal red blood cells, hemoglobin proteins do not form fibers.




Concept Check: Based on the fiber-like structures seen in part (c) of this figure, what aspect of

hemoglobin structure does a glutamic acid at the sixth


position in normal β-globin prevent? Speculate as to how the charge of this amino acid may play a role. -

ANSWER✔✔-Chapter 15 Concept Checks




Page 1/16

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FIRST PUBLISH OCTOBER 2024




Figure 15.1 At neutral pH, glutamic acid is negatively charged. Perhaps the negative


charges repel each other and prevent hemoglobin proteins from aggregating into


fiber-like structures


Figure 15.3 Example of a somatic mutation. This child has a streak of white hair. This is due to a somatic

mutation in a single cell during embryonic development. This cell continued to divide to produce a streak

of white hair.




Concept Check: Can this child with a streak of white hair transmit this


trait to his future offspring? - ANSWER✔✔-Chapter 15 Concept Checks




Figure 15.3 This trait is due to a mutation that occurred in a somatic cell, so it cannot be transmitted to

the individual's offspring.


Figure 15.6 Formation and structure of a thymine dimer.




Concept Check: Why is a thymine dimer harmful? - ANSWER✔✔-Chapter 15 Concept Checks




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Figure 15.6 A thymine dimer is harmful because it can cause an error in DNA replication that results in a

mutation.


Figure 15.8 Nucleotide excision repair in E. coli.




Concept Check: Which components of the NER system are responsible for removing the damaged DNA? -

ANSWER✔✔-Chapter 15 Concept Checks




Figure 15.8 UvrC and UvrD are responsible for removing the damaged DNA. UvrC


makes cuts on both sides of the damage, and then UvrD removes the damaged region.


Figure 15.9 An individual affected by xeroderma pigmentosum.




Concept Check: Why is this person so sensitive to sunlight? - ANSWER✔✔-Chapter 15 Concept Checks




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