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USMLE Exam| Latest Questions with 100% Correct Answers
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USMLE Exam| Latest Questions with 100% Correct Answers
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USMLE Exam| Latest Questions with100% Correct Answers
What method of bacterial resistance would be impeded by adding H+ to the
solution? - ✔ ✔ Bacterial efflux of the drug because the pump normally
needs energy that is created by a H pump
Pt has a point mutation leading to Arg for Glyc in the 375 position for gene coding
for a fibroblast growth factor receptor on chromosome 4? - ✔ ✔ Achondroplasia
Achondroplasia clinical features? - ✔ ✔ Autosomal dominant genetic
disorder leading to inhibited cartilage proliferation which leads to shortened
proximal extremities and an enlarged head with frontal bossing
Lens ectopy resulting from a mutation in FBN1 gene on chromosme 15?
- ✔ ✔ Marfan's syndrome
Bone fragility resulting from a mutation in COL1A1 gene on Chr 17 or
COL1A2 gene on Chr 7? - ✔ ✔ Osteogenesis imperfecta
t(11:22) ? - ✔ ✔ Ewing Sarcoma
,What genetic abnormalities are associated with fused or extra digits although it
can occur as isolated event? - ✔ ✔ Fused: apert syndrome from missense in
FGFR-2 on chr 10. Extra: Patau syndrome trisomy 13
Infant found to have a defective tyrosine kinase that is normally activated by CD
19 and is involved in responding to antigen exposure? - ✔ ✔ Bruton's
Agammaglobemenia
Pt has normal testosterone levels by low testosterone in seminiferous tubules
and epididymis what cells are dysfunctional? - ✔ ✔ Normal levels are generated
by leydig cells. Sertoli cells produce androgen binding protein that keeps an
increased testosterone in seminiferous tubule
Ablation of what structure can treat hyperhidrosis? - ✔ ✔ Thoracic
sympathetic trunk
What component that interacts with the uterus can be found in the
round ligament? - ✔ ✔ Inguinal canal
What 2 steps in the pathway of epinephrine production require methylation? -
✔ ✔ Norepinephrine to epinephrine and epinephrine to vanillylmandelic acid
Soft, flesh colored nodules are what in a patient with cafe au lait , intertriginous
freckling, bony lesions, iris lisch nnodules? - ✔ ✔ Benign tumor from NF1
, What pulmonary conditions are associated with hyaline membrane in the alveoli?
- ✔ ✔ ARDS and hyaline membrane disease of neonates
Bowel shows mucosal hemorrhage and patchy areas of necrosis? - ✔ ✔
Ischemic colitis
What is the enzyme in the first step of beta-oxidation? - ✔ ✔ Acyl CoA
Dehydrogenase(there is a small, medium, and large chain version)
Where is deficit if patient begins to have low glucose and no ketone body
formation >24 hours after a fast? - ✔ ✔ Beta-oxidation or Ketone body synthesis
Why are ketone bodies produced during a long fast? - ✔ ✔ Acetyl-CoA
produced exceeds the amount that can be used in TCA
What Michaelis-Menton kinetic changes with increase in enzyme concentration?
- ✔ ✔ Velocity max increases but Km doesn't change
X-ray shows a knee with almost complete loss of cartilage. What is most common
risk factor and condition? - ✔ ✔ OA and Age
What medical treatment can be given to pts with carcinoid tumors? -
✔ ✔ Octreotide it decreases the release of bioactive peptides from the tumor
What vitamin deficiency is common in pt with carcinoid syndrome? - ✔ ✔
Niacin due to excessive use of tryptophan to make serotonin
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