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Pharmacology 5334 Final Exam Questions And Accurate Answers
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Pharmacology 5334 Final Exam Questions AndAccurate Answers
PCN drug-drug interactions - Answer -aminoglycosides
-bacteriostatic antibiotics
-probenecid
Treatment for ONYCHOMYCOSIS - Answer Terbinafine (Lamisil) 1 tab daily x 3-6 months
po
Best treatment for chlamydia - Answer Aziythromycin 1gm 1x dose
or
Doxycycline 100 mg po twice a day for 7 days
Patient with vaginal candidiasis, what is the treatment? - Answer Fluconazole 150mg po
once
Treatment for uncomplicated cervical gonorrhea - Answer Ceftriaxone, 250 mg IM once,
plus azithromycin, 1 g PO once
Patient with tinea capitis, what is the TX? - Answer Very difficult to treat topically
Griseofulium po 6-8 weeks
or
Terbinafine (Lamisil) po 2-4 weeks
Narrow Spectrum PCN - Answer PCN G (procaine), PCN G (benzathine), PCN V
,Bugs they fight: GRAM(+) cocci- 1st drug of choice against Strep (pneumonia,
pharyngitis, endocarditis), Clostridium (tetanus, anthrax, gas gangrene)Neisseria,
spirochete (syphilis)
Lauren presents to the clinic and is found to have Trichomoniasis. The NP can
prescribe: -AnswerMetronidazole, 2 g PO once or
Tinidazole, 2 g PO once
Penicillinase-resistant PCN -AnswerOxacillin, Nafacillin, Dicloxacillin
Bugs they fight: Staph
Broad spectrum PCN -AnswerAmpicillin- ampiciliin/sulbactam (Unasyn)
Amoxicillin- amoxicillin/ER (Moxatog), Amoxicillin/Clavulanate(Augmentin)
Bugs they fight: Good against GRAM (-)H. influenza, e-coli, proteus mirabilis,
enterococci, salmonella and shigella
Extended Spectrum PCNs -AnswerPiperacillin/tazobactam (Zosyn)
Bugs they fight: same as broad spectrum + pseudomonas, klebsiella, bacterial fragilis
Beta-lactamase inhibitors - Answer clavulanic acid, sulbactam, tazobactam
**Can not be given on their own, only in combo with PCN's i.e.> Augmentin, Unasyn,
Zoysn
Cephalosporin Generation 1 - Answer -cephalexin
-cephazolin
-cephadoxil
**Cephlasporinase will destroy**
Not the drug of choice for active infections- good for prophylaxis prior to sx
, Cephlasporin (2nd generation) - Answer Cefuroxime-most common
Bugs they fight: h.influenza (pneumonia), otitis sinusitis, res. tract infection
Cephlasporin (3rd generation) - the answers Cefotaxime, Cefdinir, Cefixime,
Cefodoxime, Ceftaazidime, Ceftibuten, Ceftriaxone
**Can penetrate CSF fluid**
Bugs they fight: Great against GRAM (-) bacteria causing meningitis, h.influenza,
klebsiella, proteus, salmonella
Cephlasporin (4th generation) - the answer Cefepime-hospital associated pneumonia's
& Ceftolozone/tozobactam (Zerbaxa)- complicated UTI's and intraabdominal infections
Cephlasporin (5th generation) - the answer Ceftaroline (Teflaro)-MRSA
Cephalosporin and PCN - the answer Cross allergy w/PCN
Carbapenems - Answer Only 4: Imipenem, Meropenem, Ertrapenem, Doripenem
EXTREMELY broad spectrum, **only given IV**
not active against MRSA
Iminpenem-cilastatin - Answer Most effective antibiotic against anaerobic bacteria
Highly effective against Gram (+/) cocci & bacilli
Meropenem - Answer Bacterial meningitis-3m and up
Intraabdominal infections across ages
complicated skin infections
Ertrapenem (Invanz) - Answer Pelvic infections
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