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Pharmacology 5334 Module 3 Exam Questions And Answers
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Pharmacology 5334 Module 3 ExamQuestions And Answers
Maximum dose of Sumatriptan that can be administered in 1 day - Answer 200 mg
What 3 properties determine the anesthetic's ability to penetrate the axon membrane? -
Answer Lipid solubility, degree of ionization at tissue pH, molecular size
Why is epinephrine given with local anesthetics? - Answer Decreases local blood flow;
delays systemic absorption of the anesthetic; prolongs anesthesia; reduces the risk of
toxicity
Most commonly utilized local anesthetic - Response Lidocaine
What is a potential lethal response to benzocaine? - Response Methemoglobinemia
What does application guideline include in the usage of topical anesthetics? - Response
Do not wrap the site, heating of the site; do not apply to open skin; use minimum amount
to smallest site
What is the best option for menstrual migraine? - Response Low dose estrogen about 3
days prior to menses
What are the 3 major classes of opiod receptors? -Answer Mu, alpha, and delta
Which medication will reverse the effects produced by opioid agonists? -Answer
Naloxone (Narcan)
, Which medications are used for the treatment of opioid induced constipation (OIC)?
-Answer Naloxegol, methylinaltrexone, and lubiprostone
Tolerance is defined as: -Answer higher doses of a medication necessary to achieve the
same response
Dependence, physical The condition produced by the habitual taking of a drug; it is
characterized by: - Abstinence syndrome when the drug is discontinued abruptly
Abuse Use of a drug that is:
- Inconsistent with medical or social norms
Addiction A pattern of behavior characterized by:
- Compulsive use of a psychoactive substance despite physical, psychologic, or social
harm
What is the drug of choice for opioid abuse? Naltrexone
Euphoria induced by morphine: - Answer an exaggerated sense of well-being caused by
the activation of mu receptors
What medication is given nasally for migraines? - Answer Butorphanol
Describe the mechanism of NSAIDs - Answer Inhibition of the cyclo-oxygenase enzyme
Second generation Cox 2 inhibitors: - Answer suppress inflammation and cause less risk
for GI ulceration than Cox 1; increase the risk for heart disease
What medication should NOT be given with aspirin? - Answer Glucocorticoids
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