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ACNP 1 DM: Questions With Complete Answers (100%)
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ACNP 1 DM: Questions With Complete Answers (100%)
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ACNP 1 DM: Questions With Complete Answers (100%)Type 1 Insulin associated Right Ans - HLA- DR3 or HLA- DR4
Islet cell antibodies
Signs/Symptoms of DM Right Ans - Polyuria, polydipsia, polyphagia,
nocturnal enuresis, weight loss, weakness/fatigue, blurred vision, skin
infections
DM random plasma glucose Right Ans - >200 mg/dL with polyuria,
polydipsia and weight loss
DM serum fasting Right Ans - >126 mg/dL on two seperate occasions
Check fasting glucose frequency Right Ans - q 3 years for individuals over
40 or with a BMI >25
Oral glucose tolerance test Right Ans - >200 two hours post prandial
Pts with type 1 DM require Right Ans - 0.5-1.0 u/kg per day divided into
multiple doses
DM daily teaching Right Ans - Carbs 55-60%
Fat 20-30%
Fiber 25g
Protien 10-20%
Conventional split dose mixtures for insulin Right Ans - Morning dose of
insulin 2/3 NPH and 1/3 Regular
Evening dose is 1/2 NPH and 1/2 regular
Each 15 gm CHO raises BG Right Ans - 50 mg/dL
NPH Right Ans - Onset 30-60
Peak 4-10 hrs
Duration 12-24 hrs
Glarginve (lantus) Right Ans - Onset: 2-4 hrs
Expensive
, Lispro or Aspart Right Ans - Onset 5 min
Peak 1 hr
Duration 4-5 hrs
Regular Right Ans - Onset 30-45 min
Peak 3-4 hrs
Duration 4-10 hrs
Metabolic Syndrome Right Ans - Waist circumference >40 inches- 35 in
women
BP >135/85
Triglycerides >150
FBG >100
HDL <40 in men 50 in women
Prediabetes Right Ans - FPG 100-125
2-h plasma glucose 140-199
A1c 5.7-6.4
Goal Hb A1c Right Ans - <7.0%, test 2 x annually or quarterly with changes
Biguanides example Right Ans - Metformin
First line treatment in DM type 2 Right Ans - Metformin, no hypo and helps
weight loss
Metformin contraindicated in Right Ans - Renal failure, hold with
radioactive dye
Second generation sulfonylureas Right Ans - Glipizide, glyburide,
glimepiride
Sulfonyleureas can causes Right Ans - hypoglycemia, wt gain
the mechanism of action of sulfonylureas is as:
a. an antagonist of insulin receptor site activity
b. a product that enhances insulin release
c. a facilitator of renal glucose excretion
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