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Lippincott Illustrated Reviews: Pharmacology 8th Edition by Karen Whalen||ISBN NO:10,1975170555-Test Bank GUARANTEED A+ WITH RATIONALES$17.99
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Lippincott Illustrated Reviews: Pharmacology 8th Edition by Karen Whalen||ISBN NO:10,1975170555-Test Bank GUARANTEED A+ WITH RATIONALES
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Course
Advanced pharmacology
Institution
Advanced Pharmacology
Lippincott Illustrated Reviews: Pharmacology 8th Edition
by Karen Whalen||ISBN NO:10,1975170555-Test Bank
GUARANTEED A+ WITH RATIONALES
)
1. What is the primary action of beta-blockers?
o A) Increase heart rate
o B) Decrease heart rate and contractility
o C) Dilate blood vessels
o D) Incre...
Lippincott Illustrated Reviews: Pharmacology 8th Edition
by Karen Whalen||ISBN NO:10,1975170555-Test Bank
GUARANTEED A+ WITH RATIONALES
)
1. What is the primary action of beta-blockers?
o A) Increase heart rate
o B) Decrease heart rate and contractility
o C) Dilate blood vessels
o D) Increase respiratory rate
o Answer: B) Decrease heart rate and contractility
Rationale: Beta-blockers primarily block the effects of adrenaline on the beta
receptors, leading to a decrease in heart rate and myocardial contractility.
2. Which of the following is an example of a loop diuretic?
o A) Hydrochlorothiazide
o B) Furosemide
o C) Spironolactone
o D) Mannitol
o Answer: B) Furosemide
Rationale: Furosemide is a loop diuretic that acts on the ascending loop of Henle
in the kidney to increase urine production.
3. What is the mechanism of action of ACE inhibitors?
o A) Block beta-adrenergic receptors
o B) Inhibit angiotensin-converting enzyme
o C) Promote aldosterone release
o D) Increase calcium influx
o Answer: B) Inhibit angiotensin-converting enzyme
Rationale: ACE inhibitors prevent the conversion of angiotensin I to angiotensin
II, leading to vasodilation and reduced blood pressure.
4. Which of the following medications is considered a first-line treatment for
hypertension?
o A) Metoprolol
o B) Amlodipine
o C) Hydrochlorothiazide
o D) Lisinopril
o Answer: C) Hydrochlorothiazide
Rationale: Hydrochlorothiazide is often used as a first-line treatment for
hypertension due to its efficacy and safety profile.
5. What is the main effect of anticoagulants?
o A) Increase blood pressure
o B) Prevent blood clotting
o C) Lower cholesterol levels
o D) Dilate blood vessels
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o Answer: B) Prevent blood clotting
Rationale: Anticoagulants reduce the formation of blood clots by inhibiting
various factors in the coagulation cascade.
6. Which of the following drugs is an opioid analgesic?
o A) Ibuprofen
o B) Acetaminophen
o C) Morphine
o D) Aspirin
o Answer: C) Morphine
Rationale: Morphine is a strong opioid analgesic used to relieve moderate to
severe pain.
7. What is the primary action of statins?
o A) Increase blood glucose levels
o B) Lower blood pressure
o C) Lower cholesterol levels
o D) Increase heart rate
o Answer: C) Lower cholesterol levels
Rationale: Statins inhibit HMG-CoA reductase, an enzyme involved in
cholesterol synthesis, leading to lower LDL cholesterol levels.
8. Which class of drugs is used to treat asthma by dilating the airways?
o A) Antihistamines
o B) Corticosteroids
o C) Beta-2 agonists
o D) Mucolytics
o Answer: C) Beta-2 agonists
Rationale: Beta-2 agonists stimulate receptors in the lungs, leading to
bronchodilation and improved airflow.
9. Which medication is commonly used to manage type 2 diabetes by increasing insulin
sensitivity?
o A) Metformin
o B) Insulin
o C) Glipizide
o D) Acarbose
o Answer: A) Metformin
Rationale: Metformin enhances insulin sensitivity and decreases hepatic glucose
production, making it a first-line treatment for type 2 diabetes.
10. What is a major side effect of glucocorticoids?
o A) Hypoglycemia
o B) Weight loss
o C) Osteoporosis
o D) Bradycardia
o Answer: C) Osteoporosis
Rationale: Long-term use of glucocorticoids can lead to decreased bone density,
increasing the risk of osteoporosis.
11. Which of the following is an example of a thrombolytic agent?
o A) Warfarin
, 3|Page
o B) Aspirin
o C) Alteplase
o D) Clopidogrel
o Answer: C) Alteplase
Rationale: Alteplase is a thrombolytic agent used to dissolve blood clots in
conditions like acute myocardial infarction and stroke.
12. What is the action of proton pump inhibitors (PPIs)?
o A) Increase gastric acid production
o B) Inhibit the secretion of gastric acid
o C) Neutralize gastric acid
o D) Stimulate gastric motility
o Answer: B) Inhibit the secretion of gastric acid
Rationale: PPIs block the proton pump in gastric parietal cells, leading to
decreased acid secretion and relief from acid-related disorders.
13. Which class of drugs is often used to treat hyperlipidemia?
o A) Diuretics
o B) Beta-blockers
o C) Statins
o D) ACE inhibitors
o Answer: C) Statins
Rationale: Statins are the most commonly prescribed medications for lowering
lipid levels, specifically LDL cholesterol.
14. What is the mechanism of action of selective serotonin reuptake inhibitors (SSRIs)?
o A) Inhibit serotonin synthesis
o B) Block serotonin receptors
o C) Inhibit serotonin reuptake
o D) Increase dopamine levels
o Answer: C) Inhibit serotonin reuptake
Rationale: SSRIs prevent the reabsorption of serotonin in the brain, increasing its
availability and improving mood.
15. Which medication is used as an antidote for acetaminophen overdose?
o A) Naloxone
o B) N-acetylcysteine
o C) Atropine
o D) Flumazenil
o Answer: B) N-acetylcysteine
Rationale: N-acetylcysteine replenishes glutathione stores and helps prevent liver
damage in cases of acetaminophen overdose.
16. What is the primary therapeutic use of aspirin?
o A) Pain relief
o B) Anti-inflammatory
o C) Antipyretic
o D) All of the above
o Answer: D) All of the above
Rationale: Aspirin has analgesic, anti-inflammatory, and antipyretic properties,
making it useful for various conditions.
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