PHAR 100 – Midterm Questions And Answers Guaranteed Success.
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PHAR 100 -
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PHAR 100 -
PHAR 100 – Midterm Questions And Answers Guaranteed Success.
Key historical influences to pharmacology - correct answer. -Civilizations: Greece, Egypt, China
-Poison: Curare, Ergot
-Religion
Why was zinc oxide an important compound - correct answer. currently found in ...
PHAR 100 – Midterm Questions And
Answers Guaranteed Success.
Key historical influences to pharmacology - correct answer. -Civilizations: Greece,
Egypt, China
-Poison: Curare, Ergot
-Religion
Why was zinc oxide an important compound - correct answer. currently found in
topical creams (i.e. calamine)
What did ancient greece, egypt, and china contribute - correct answer. greece -
opium - codeine + morphine
egypt - senna, purgatives
china - ephedrine (asthma)
What is Curare's function as a poison + pharmaceutical - correct answer. poison =
paralysis/death, drug = anesthesia
What is Ergot's function as a poison + pharmaceutical - correct answer. poison =
mental frenzy, burning limbs, uterus contraction
pharm = ergotamine: treats migraines, ergonovine: arrests uterine bleeding after
childbirth
What did Paul Ehrlich design - correct answer. organoarsenicals - binds to parasites
= cure for syphillis
Name 9 basic drug development steps - correct answer. 1- drug discovery
2- pre-clinical
3- clinical trial: initial steps
4- phase 1: young healthy people
5- phase 2: people affected by disesase (~500 ppl)
, 6- phase 3: people affected by disease (1000+)
7- Health Canda review
8- Manufacturing
9 - Phase 4: tests over long period/taken concurrently w/ other drugs
Name 6 advertising techniques - correct answer. -before/after
-fear
-offer an easy solution
-attention catching
-celeb endorsement
-discredit other manufacturers
Name 3 drug targets - correct answer. -receptors
-chemical rxn
-physical/chemical forces
Explain ED50 - correct answer. The dose that gives 50% of max. response
What are factors that contribute to the removal of the drug from the body - correct
answer. Excretion: kidney (80%+ of drugs), must be water soluble (conversion
needed) Biotransformation in liver, metabolism, feces (GI tract), saliva, sweat, milk,
Define efficacy - correct answer. the max pharmacological response that can be
produced by a specific drug in that bio system
Define potency - correct answer. The dose of a drug required to produce a certain
response (usually 50% of max)
Define therapeutic range - correct answer. range of doses that keep [blood] of a
drug above the [minimum] to produce desirable response, but below the [toxic
response]
What are the 4 major processes of pharmacokinetics - correct answer. 1-absorption
2-distribution
3-metabolism
4-excretion
Name 3 general main routes of administration - correct answer. 1. Topical
2. Enteral admin (enter blood through GI tract)
3. Parental admin (injected into bloodstream)
What are the 3 topical administration methods - correct answer. 1. on skin
2. through skin (transdermal)
3. inhalation (rapidly absorbed by lungs)
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