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Nurs 3315 Module A Exam Questions And Already Passed Answers.

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  • NURS 3315

Cumulation - Answer Process by which blood levels of a drug build up. Increases therapeutic and toxic effects. May result from poor elimination due to slow metabolism, binding the drug to plasma proteins or inhibition of excretion as occurs in sufferers of a kidney disease Off-Label - Answ...

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  • November 3, 2024
  • 7
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NURS 3315
  • NURS 3315
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Nurs 3315 Module A Exam Questions
And Already Passed Answers.
Cumulation - Answer Process by which blood levels of a drug build up.

Increases therapeutic and toxic effects.

May result from poor elimination due to slow metabolism, binding the drug to plasma proteins or
inhibition of excretion as occurs in sufferers of a kidney disease



Off-Label - Answer when a drug is prescribed for a different purpose than what the FDA has approved



Therapeutic Levels - Answer Toxicity: occurs if the peak blood level of the drug is too high

Peak: Highest blood level of a drug

Trough: lowest blood level of a drug



Pharmacodynamic Changes in Aging - Answer Alterations in receptors

Beta Blockers less effective

Warfarin, CNS Depressants more intense

More adverse drug reactions

Mostly dose related

Usually non-specific (dizziness, cognitive impairment)



Considerations in Pregnancy: Lactation - Answer Contraindicated:

Illicit Drugs

Anticancer agents/immunosuppressants

Atenolol

Bromocriptine

Ergotamine

Lithium

Nicotine

, Radioactive compound



COX-1 inhibitors (First Gen NSAIDS) - Answer indicatio mild-moderate pain, ns:fever, inflammation (RA,
OA)

MOA: interferes with COX-1 which promote synthesis of prostaglandins that have primarily beneficial
effects on bodily function

teaching: AE include Gi side effects (dyspepsia, heartburn, nausea, gastric or duodenal mucosal
injury/ulceration). Alert for increased risk of bleeding. Risk for thrombotic CV event

Other Things to Know:

Aspirin-like drug but few

GI, Renal and hemorrhagic effects.

Inhibition of cox-1+2, inhibition is reversible (Unlike aspirin)

NO PROTECTION AGAIST MI OR STROKE



COX-2 inhibitors (Celecoxib/Celebrex) - Answer indications: OA/RA, acute pain symptoms, ankylosing
spondylitis, primary dysmenorrhea

MOA: interferes with COX-2 which promote synthesis of prostaglandins involved in inflammatory
processes

teaching: AE include headache, diarrhea, fatigue, dizziness, hypertension, do not use if sulfa allergy

Other Things to Know:

Little effect on platelet function and lower risk for GI side effects

Can't be used with sulfa allergy

Can impair renal function and cause hypertension and edema (bc blocks prostaglandins)

Increased risk of MI + Stroke, so its the last choice for long-term pain



Aspirin (Salicylic Acid) - Answer indications: headahce, algia, arthritis, pleurisy, pericarditis, lupus,
antipyretic action. LOW dose aspirin (81 or 325mg) for thromboprevention. Pain, fever, arthritis doses
higher.

contraindications: children under 12 - reyes syndrome (neurologic deficits, coma, liver damage. Swelling
of the liver and brain)

adverse/side effects: increased HR, tinnitus, N/V/D, sweat, thirst, hyper/hypoglycemia, renal impairment

warnings: salicylism (tinnitus, sweating, headache, dizziness)

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