PHMY 610 EXAM 1 ADAPTIVE IMMUNE
RESPONSE {FANG} TEST QUESTIONS
AND ANSWERS
what is a molecule that could be recognised by lymphocytes or antibodies?
antigen
what are antigens that are capable of inducing an immune response in the host
organism?
immunogens
what are the cells that capture microbial antigens and display them for
recognition by T lymphocytes?
antigen presenting cells
-
what are the kinds of APCs?
professional: dendritic cells, macrophages, B cells
non-professional: all nucleated cells
what are the functions of APCs?
- present peptides for recognition by T cells; first signal
- express second signal for T cell activation
APCs express major ________ ________ ________ molecules.
major histocompatibility complex
, what are membrane proteins expressed on APCs and display peptide antigens
for recognition by T lymphocytes?
MHC molecules
where are MHC molecules found?
mammals
human MHC proteins are called what? what do they do?
human leukocyte antigens
they cause rejection after transplantation
MHC locus contains two types of polymorphic genes, what are they?
class I and class II
which cells are considered class I MHC molecules?
non-professional: all nucleated cells (APCs)
which cells are considered class II MHC molecules?
professional APCs: dendritic cells, macrophages, B cells
MHC locus contains many nonpolymorphic genes, what class are they?
class III
what is MHC restriction?
T lymphocytes of a specific individual can see peptides only when these
peptides are display by that individuals MHC molecules
which cells are present in tissues in contact with the external environment and
microbes that breach the epithelial barriers and enter the body are captured
by these?
dendritic cells
what are properties of MHC genes?
- highly polymorphic
- codominantly express
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller luzlinkuz. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $11.49. You're not tied to anything after your purchase.