Nuclear Medicine Board Review | Questions and
answers with 100% correct solutions | Graded A+
Renal Imaging with ACE Inhibitors ✔✔most common: Capoten (captopril) and Vasotec
(enalaprit) discontinue daily use 3-7 days prior
well hydrated and void before procedure
1 hour before RP administration
Tc99m Pentetate ✔✔cleared by glomerular filtration, binds to renal
parenchyma renal uptake is proportional to GFR
rapid clearance rate, useful in demonstrating glomerular filtration rate as well as relative blood flow
to each kidney
Tc99m MAG3 ✔✔excreted from kidneys via tubular secretion, used to measure renal tubular
flow high first-pass extraction fraction and rapid plasma clearance used to assess effective renal
plasma flow (ERPF)
Tc99m DMSA ✔✔succimer binds to the tubules in the renal
cortex cortical imaging
50% of RP bound within 2 hours of administration
tracer remains fixed in renal parenchyma for a relatively long period of time, therefore most useful
for imaging space-occupying lesions (cysts, tumors) or gross renal anatomy
,Radionuclide cystography ✔✔evaluation of vesicoureteral reflux
most common in children
indirect: IV administration of renal agent, after it is administered, patient is asked to void while being
imaged
direct: cath patient, connect to 1mci iv saline/tc99m pertechnetate; image while filling bladder,
discontinue administration when bladder capacity is reached
Adrenal Imaging ✔✔I MIBG methyliodbenzyl
guanidine prep: Luglos given to block thyroid 123 - 10 mCi
131 - .5mCi
goes to liver/spleen/heart
free iodine may be in urine
Liver/spleen ✔✔tc99m sulfur collod
average 1um in size
liver - 85%
spleen - 10%
BM-5%
5 t010 mci
image 10-15 minutes post injection
Detection of Liver Hemangioma ✔✔cavernous hemangioma
, tc99m labeled RBC's
20-25 mCi
abnormal: decreased or normal perfusion on flow, but increased on delays
Lung quantitation ✔✔access patients before lung resection / monitor result ion of PE's
55% to right
45% to left
quantitation of blood flow drawn with regions
1 to 4 mCi TC99m MAA IV
Mo 99 ✔✔67 hour half life
740 KeV
F 18 ✔✔110 min half life
511 KeV
positron emission ✔✔when a proton is converted to a neutron, a position, a neutrino and energy
Th 201 ✔✔t 1/2 = 73 hours
69 - 81 KeV
accelerator produced
calibration of survey meters ✔✔daily reference checks using long-lived sourced
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