NBCRNA Actual Exam Solved
Reviewed Combined Questions
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1. Which type of pneumocystis produce surfactant? - ANSWER
2. Three types of pneumocytes? - ANSWER
type 1 - cover 80% of alveolar surface
type...
9. Neostigmine is a... - ANSWER cholinesterase inhibitor that reversibly
binds to acetylcholinesterase at the NMJ - this inhibits acetylcholine
hydrolysis allowing more ACh to compete with the NMBA at the nicotinic
receptor
- competitve antagonism!
10.Produces reversible inhibition of AchE by forming a carbamyl ester complex
at esteratic site? - ANSWER Neostigmine
pridostigmine
physostigmine
11.Forms an electrostatic bond at the anionic site and a noncovalent hydrogen
bond at the esteratic site. - ANSWER Edrophonium
, - hydrogen bonds are weak so DoA is short
12.Produces non-reversible inhibition of AchE by forming a stable complex
with the esteratic site. New acetylcholinesterase must be synthesized,
which explains this extended DoA.... - ANSWER Organophosphates
13.Match the acetylcholinesterase inhibitor to its dose:
Neostigmine
Edrophonium
- lipophilic
- easily diffuse lipid membranes like BBB, GI tract and placenta
21.Robinul is a ? - ANSWER quaternary ammonium derivate that ionizes
in the plasma
- doesn't cross easily
22.What is cycloplegia? what causes it? - ANSWER paralysis of the ciliary
muscle in the eye, resulting in the loss of accommodation
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