Class notes
Lupus Nursing School Notes
- Course
- NUR 211
- Institution
- Wilkes Community College
The MUST KNOW points concerning “Lupus”, for nursing school. Get all the must know material condensed down for nursing exams and NCLEX!
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Hus⑧
· ⑧ · O
· . ⑧
o
O
O
· O
O O ·
·
* SLE
multisystem inflamm autoimmune disease
:
.
affects skin joints pleura pericardium renal hematologic
-
, , , , ,
neuro
*
unpredictable course (alt remission / exacerbation) .
-
Black. Asian . Hispanic ,
Native Am .,
Pacific Islander =
↑ risk
>
women = risk lage15-45)
Patho poss genetics (HLA-DR2/DR3)
=
:
- unknown ;
-hormones ( worse wh menses oral contracept during/after , , pregt
*Worse in
postpartum
Epstein Barr hyperact.
-
=
Stim immune .
Environmental (sun/UV/chemicals toxins silica dust)
-
-
,
Drugs (sulfa diuretics tetracycline)
-
, ,
*
After months -
urs
*
Body makes various antibodies against nucleic acid , erythro coag proteins lymphocytes plts
., , ,
*
Autoimmune reactions againstCell nucleus (DNA)
-
* Inflamm = tissue destruction
↳ overaggressive autoimmune response (B/c B$T cells)
* SLE Type Ill hypersens response
=
.
· Manifestations * varies from mild-rapid progressive (no same pattern
Common tissue involved Skin/muscle liking of lungs heart nervous tissue Kidneys
-
:
, , ,
,
Askin-fever-weight loss joint pain fatigue Pneumonia
-
-
Grow back
rash can
alopecial Butterflyrash-discoid/palmar erythema mucosal ukers -proteinuria
-
-
-
Often 1st
Glomerulonephritis
-Endo/MyolPeri-carditis-PE-Rayhands Phenomenon hematuria
-
-
Symp .
arthritis stroke-Seizures Periph Neuropathy psychosis anemia
- - -
-
.
cause deform I .
/Swan neck sublux) Splenomegaly Thrombocytopenia Abd pain/diarrhea/NI--menstrual abhorm
-
- -
.
,
skin lesions (sun exposed areas photosensativity
-
-
chronic cut Lupus discoid lesion scalp face
· : -
.
bacute cut lupus red-ring shaped lesion
· .
:
> not thick/scaly
cute lupus lesion when "active"
· Butterfly rash ("Malar Rash"
: =
-tachypnea-cough pleurisy-dysrythmia Secondary antiphospholipid Synd (APS)
- -
.
I
&
End Stage Venal disease (ESRD) leukopenia ↳ coag. disorder 14 risk stroke gangrene,
- -
,
heart attack)
* Resistant to Blood thinning from Aspirin
· TX for Lupus Kidney Probs
1) corticosteroids Immunosuppr.
lazathioprine ; cyclosporine ; Oral Prednisone ; IV Methylprednisolone
2) Monoclonal Antibody
/belimumab-Benlystal
'voclosporin-Lupkynis) -
Stop T cell
*
Hydroxychloroquine ↓ risk for clots
:
BIC Asprin wont
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