Exam (elaborations)
BIO 340 (Genetics) EXAM QUESTIONS CORRECTLY ANSWERED AND VERIFIED ARIZONA STATE UNIVERSITY
- Course
- Institution
BIO 340 (Genetics) EXAM QUESTIONS CORRECTLY ANSWERED AND VERIFIED ARIZONA STATE UNIVERSITY
[Show more]
Content preview
BIO 340 (Genetics) EXAM QUESTIONSCORRECTLY ANSWERED AND VERIFIED
ARIZONA STATE UNIVERSITY.
Pyrimidine dimers are produced by
Correct Answer -the formation of one or two additional covalent bonds
between adjacent pyrimidine nucleotides
ionizing radiation
Correct Answer -1. can cause double stranded breaks in DNA which are
difficult to repair
2. Directly attack deoxyribose in the backbone
3. Can generate reactive oxygen species
examples of ionizing radiation include
Correct Answer -x-rays and y radiation
polygenic
Correct Answer -Most human genetic diseases are polygenic, caused by
variation in several genes
monogenic diseases
Correct Answer -disorders caused by a mutation in a single gene
Which of the following is not result of strand slippage during DNA
replication?
,A. Nucleotide insertions
B. Expansion of trinucleotide repeat sequences
C. Pyrimidine dimers
Correct Answer -Pyrimidine dimers
Systems repairing single-strand breaks include:
Correct Answer -mismatch repair (MMR)
base excision repair (BER)
nucleotide excision repair (NER)
Double-strand breaks (DSBs)
What are direct reversal repair systems?
Correct Answer -chemical reactions that reverse the damage returning DNA
to its proper state
Single strand damage repair relies on what?
Correct Answer -The intact of complementary strand to guide repair
mismatch repair
Correct Answer -The cellular process that uses special enzymes to fix
incorrectly paired nucleotides.
Example: methyl-directed pathway (E.Coli)
Photoreactivation
Correct Answer -uses light to activate repair enzymes
,UV irradiation
Correct Answer -Causes the formation of thymine dimers
Which enzyme is involved in photoreactivation?
Correct Answer -Photolyase
What does photolyase do in photoreactivation?
Correct Answer -Breaks thymine dimers
Double stranded break repair result in
Correct Answer -chromosomal rearrangements, cancer, cell death
Two path ways involved in double stranded break repair are
Correct Answer -- non homologous end joining
- homologous recombination repair
What are the 2 products of holiday junctions that are resolved?
Correct Answer -Non crossover products and crossover products
The non crossing product is
Correct Answer -A patch product because it's got a small size of the nuclear
casting from a different strand
, Generalized recombination
Correct Answer -requires that the two recombining molecules have a
considerable stretch of homologous DNA sequences
site-specific recombination
Correct Answer -requires very little sequence homology between the
recombining DNA molecules
- but does require short sequence recognized by recombination enzyme
What are two site specifics recombinations?
Correct Answer -Tyrosine recombinase and serine recombinase
What is viral recombination?
Correct Answer -Switching of reverse transcriptase or DNA polymerase
between two different templates during reverse transcription
Viral recombination is essential for what?
Correct Answer -Virus evolution
Transposons
Correct Answer -segments of DNA that can move from one region of DNA to
another
Transposons carry what?
Correct Answer -A gene that encodes for an enzyme called transposase
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller saraciousstuvia. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $16.49. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
72042 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now