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Test Bank for Lehninger Principles of Biochemistry 8th Edition by David L. Nelson||ISBN NO:9781319228002||Complete Guide A+||Latest Update 2024/2025 WITH RATIONALS guaranteed +

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Principles of Biochemistry

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Principles Of Biochemistry

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biochemistry
test bank for lehninger principles of biochemistry
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Institution Principles of Biochemistry
Course Principles of Biochemistry

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Test Bank for Lehninger
Principles of Biochemistry 8th
Edition by David L. Nelson||ISBN
NO:9781319228002||Complete
Guide A+||Latest Update
2024/2025 WITH RATIONALS
guaranteed +

,1|Page

Test Bank for Lehninger Principles of Biochemistry 8th
Edition by David L. Nelson||ISBN NO:9781319228002||Complete
Guide A+||Latest Update 2024/2025 WITH RATIONALS
guaranteed +
1. Which of the following is the main function of enzymes in biochemical
reactions?

• A) To provide energy for the reaction
• B) To increase the rate of the reaction
• C) To alter the equilibrium constant
• D) To lower the activation energy of the reaction

Answer: B) To increase the rate of the reaction
Rationale: Enzymes are biological catalysts that speed up biochemical reactions by lowering the
activation energy, which results in a faster reaction rate.

2. Which coenzyme is required for the transfer of acyl groups in metabolic
reactions?

• A) NAD+
• B) Coenzyme A
• C) FAD
• D) Biotin

Answer: B) Coenzyme A
Rationale: Coenzyme A is essential in the transfer of acyl groups, playing a critical role in
reactions such as the citric acid cycle and fatty acid metabolism.

3. Which of the following statements about the citric acid cycle is true?

• A) It takes place in the cytoplasm of the cell
• B) ATP is directly produced in the cycle via substrate-level phosphorylation
• C) It is primarily responsible for the production of glucose
• D) NADH is not generated during the cycle

,2|Page

Answer: B) ATP is directly produced in the cycle via substrate-level phosphorylation
Rationale: The citric acid cycle generates ATP through substrate-level phosphorylation,
particularly in the reaction involving succinyl-CoA.

4. Which type of bonding is primarily responsible for the stability of the alpha-
helix structure in proteins?

• A) Hydrogen bonds
• B) Ionic bonds
• C) Disulfide bonds
• D) Hydrophobic interactions

Answer: A) Hydrogen bonds
Rationale: The alpha-helix structure in proteins is stabilized by hydrogen bonds between the
carbonyl oxygen of one amino acid and the amide hydrogen of another.

5. Which of the following enzymes is responsible for DNA replication?

• A) RNA polymerase
• B) DNA ligase
• C) DNA polymerase
• D) Helicase

Answer: C) DNA polymerase
Rationale: DNA polymerase catalyzes the addition of nucleotides to the growing DNA strand
during DNA replication.

6. What role do ribosomes play in the cell?

• A) Synthesizing DNA
• B) Synthesizing proteins
• C) Synthesizing RNA
• D) Synthesizing lipids

Answer: B) Synthesizing proteins
Rationale: Ribosomes are the cellular machinery that synthesizes proteins by translating mRNA
into amino acid sequences.

7. Which is a primary function of ATP in metabolism?

, 3|Page

• A) Store genetic information
• B) Provide energy for cellular processes
• C) Serve as a coenzyme for protein synthesis
• D) Regulate enzyme activity

Answer: B) Provide energy for cellular processes
Rationale: ATP serves as the primary energy currency in cells, providing energy for reactions
such as protein synthesis and muscle contraction.

8. Which vitamin is a cofactor for carboxylation reactions?

• A) Vitamin B1 (Thiamine)
• B) Vitamin B7 (Biotin)
• C) Vitamin C (Ascorbic acid)
• D) Vitamin B12 (Cobalamin)

Answer: B) Vitamin B7 (Biotin)
Rationale: Biotin is a coenzyme for enzymes involved in carboxylation reactions, such as
pyruvate carboxylase.

9. Which molecule is primarily responsible for the storage of genetic information
in the cell?

• A) RNA
• B) Proteins
• C) DNA
• D) Carbohydrates

Answer: C) DNA
Rationale: DNA stores genetic information and is the template for RNA synthesis, which directs
protein synthesis.

10. In glycolysis, which enzyme catalyzes the rate-limiting step?

• A) Hexokinase
• B) Phosphofructokinase-1 (PFK-1)
• C) Pyruvate kinase
• D) Aldolase

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Exam (elaborations)

Test Bank for Lehninger Principles of Biochemistry 8th Edition by David L. Nelson||ISBN NO:9781319228002||Complete Guide A+||Latest Update 2024/2025 WITH RATIONALS guaranteed +

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